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Is That DNA Dangerous?

Codon

It is relatively straightforward to detect the first threat―creating a virus from scratch using synthetic DNA—by searching for small fragments of known viral DNA sequences in a customer’s order. This incident spurred new laws to restrict the sale of bacteria or viruses. Journalists gather outside No.

DNA 85
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Can Global Genomic Surveillance Forecast the Next Pandemic?

PLOS: DNA Science

A Novel Virus Appears In retrospect, everything unfolded with astonishing speed. Did it there either recombine with another virus on its own, or inspire a manipulation of another virus of a key part of the spike gene, seeding the pandemic through a “lab leak?” Work on vaccines ensued too. It closed a year ago.

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Defense-Forward Biosecurity

Codon

When doctors sequenced the DNA and RNA found in Alice’s blood and synovial fluid—the liquid that surrounds and lubricates joints—they found abnormally low levels of genes encoding iron-storing proteins and high levels of epidermal growth factor receptor RNA. At least nine laboratories outside the U.S.

DNA 90
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Scientists discover new antiviral defense system in bacteria

Broad Institute

It’s been very exciting to integrate genetics, bioinformatics, biochemistry, and structural biology approaches in one study to understand this fascinating molecular system.” Most known bacterial defense systems work by sensing viral DNA or RNA, or cellular stress due to the infection. The finding was striking and unprecedented.

DNA 52
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Synthetic biology tools advancing and accelerating drug discovery efforts

Drug Discovery World

Gene-to-antibody production begins with scientists entering antibody sequences as starting material, after which bioinformatics tools filter out potentially non-viable sequences. It’s now possible to programme cell-free systems to make RNA and proteins that interact with each other,” Dr Laohakunakorn continues.

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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

Made from a Cas9 nickase (the histidine at amino acid position 840 is swapped for an alanine) fused to a reverse transcriptase enzyme (which makes DNA from RNA; transcription in reverse), prime editing clinical trials are expected to begin by 2025. link ) INSPECTR is a diagnostic tool to detect tiny amounts of viral RNA at room temperature.

DNA 52
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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

Made from a Cas9 nickase (the histidine at amino acid position 840 is swapped for an alanine) fused to a reverse transcriptase enzyme (which makes DNA from RNA; transcription in reverse), prime editing clinical trials are expected to begin by 2025. link ) INSPECTR is a diagnostic tool to detect tiny amounts of viral RNA at room temperature.

DNA 52