Drug Discovery World

AUGUST 21, 2024

Dr Andrea O’Hara, Senior Product Manager at Azenta Life Sciences asks why integration site analysis (ISA) is critical for the safety and efficacy of viral vectors for gene therapy. Cell and gene therapies have revolutionised how clinicians treat a variety of diseases including cancer, blindness, and metabolic disorders.

Therapies 148

Therapies Bioinformatics DNA FDA 148

SCIENMAG: Medicine & Health

JULY 13, 2023

Rensselaer Polytechnic Institute’s Catherine Royer, Constellation Chair Professor of Bioinformatics and Biocomputation at the Shirley Ann Jackson, Ph.D.

Bioinformatics 87

Bioinformatics Research Science 87

Practical Cheminformatics

JANUARY 16, 2024

Following up on Part I and Part II, the third post in this series is a collection of review articles published in 2023 that I found helpful.

Targeted Protein Degradation 141

Targeted Protein Degradation Small Molecule Computational Chemistry Bioinformatics 141

Broad Institute

MARCH 8, 2024

Organizing Committee By Rose Circeo March 8, 2024 Breadcrumb Home Organizing Committee Sumaiya Iqbal, Co-chair Group Leader, Bioinformatics and Computational Biology, CDoT Wengong Jin, Co-chair Postdoc, Eric and Wendy Schmidt Center Holly Soutter, General Committee Member Director, Biochemistry and Biophysics, CDoT Eric Sigel, General Committee Member (..)

Bioinformatics 52

Bioinformatics Science Research Drugs 52

Broad Institute

MARCH 8, 2024

Organizing Committee By Rose Circeo March 8, 2024 Breadcrumb Home Organizing Committee Sumaiya Iqbal, Co-chair Group Leader, Bioinformatics and Computational Biology, CDoT Wengong Jin, Co-chair Postdoc, Eric and Wendy Schmidt Center Holly Soutter, General Committee Member Director, Biochemistry and Biophysics, CDoT Eric Sigel, General Committee Member (..)

Bioinformatics 52

Bioinformatics Science Research Drugs 52

Drug Discovery World

AUGUST 29, 2022

Yahya Anvar, Head of Data Science Okra.AI Yahya Anvar, Head of Data Science Okra.AI. Dr Navar holds a PhD in Medicine from Leiden University, and an MSc in Bioinformatics and Artificial Intelligence from Brunel University. . The event will take place on 4-5 Oct, London Excel, UK and additional topics will include: .

Bioinformatics 130

Bioinformatics Biosimilars Drugs Science 130

Drug Discovery World

NOVEMBER 30, 2023

Cell and gene therapy developer eXmoor pharma has hired Matthew Paterson as the company’s first Chief Commercial Officer, moving on from 18 years at Quotient Sciences. Thierry Van Nieuwenhove has become the new Chief Executive Officer (CEO) for Quotient Sciences , succeeding Mark Egerton, who is retiring.

Bioinformatics 130

Bioinformatics Drugs Engineering Science 130

The Open Targets Blog

OCTOBER 31, 2023

Business Analyst | Cole Devries, Lead Cloud Architect | Gayathri Radhakrishnan, Senior Quality Assurance Engineer | Hannah Stogsdill, UI Designer | Mark Cunningham, Technical Project Manager | Nahom Tesfatsion, FE Developer | Shawn Wang, Senior Backend Developer | Sowmya Karavadi, DevOps Engineer | Subhashini Jagu, NCI Federal Lead | Valentina Epishina, (..)

Bioinformatics 69

Bioinformatics Engineering FDA Clinical Trials 69

Drug Discovery World

DECEMBER 7, 2023

The group examined barriers to translating basic science into effective therapies for MND and suggested guiding principles for future research. A parallel funding scheme to support data science and AI/machine learning approaches to repurposed drug candidate identification in MND will also be made available through the programme.

Bioinformatics 130

Bioinformatics Clinical Trials Drugs Trials 130

SCIENMAG: Medicine & Health

AUGUST 7, 2023

” This project advances property-controlled molecule generation.

Bioinformatics 71

Bioinformatics Research Science 71

Drug Discovery World

SEPTEMBER 14, 2023

Enabling the discovery and development of novel mRNA-based cancer vaccines by leveraging Moderna’s knowledge of mRNA science and customised information from Immatics’ wealth of tumour and normal tissue data, which is included in XPRESIDENT, the company’s target discovery platform, and XCUBE, the company’s bioinformatics and AI platform.

Vaccine 130

Vaccine Bioinformatics Clinical Trials Therapies 130

Drug Discovery World

NOVEMBER 17, 2022

Distinctive inflammatory signature . As part of the study, RNA sequencing was conducted using blood samples from 152 patients with symptoms of post-treatment Lyme disease to measure their immune response. .

Disease 130

Disease RNA Immune Response Bioinformatics 130

Broad Institute

AUGUST 7, 2024

At the Broad, he directs the Cancer Genome Computational Analysis Group , and he is a professor of pathology at Harvard Medical School and director of bioinformatics at Massachusetts General Hospital. Chan School of Public Health and Harvard University’s Faculty of Arts and Sciences, and a Howard Hughes Medical Institute investigator.

Medical Schools 90

Medical Schools Hospitals Bioinformatics Vaccine 90

Drug Discovery World

JULY 27, 2023

Most TSAs we do are for pharmaceutical companies, such as drug therapeutics, but TSAs are also applicable to other industries including veterinary science and agrochemicals.” Roberts notes that although bioinformatics is the basis of a TSA, it is only the start.

Bioinformatics 130

Bioinformatics Pharmaceutical Companies Clinical Trials Drugs 130

Drug Discovery World

OCTOBER 20, 2023

The acquisition of Olink underscores the profound impact that proteomics is having as our customers continue to advance life science research and precision medicine,” said Marc Casper, Chairman, President and Chief Executive Officer of Thermo Fisher.

DNA 130

DNA Clinical Trials Engineering Bioinformatics 130

Drug Discovery World

OCTOBER 3, 2022

Dr Yahya Anvar, Head of Data Science, OKRA.ai He holds a PhD in Medicine from Leiden University, and an MSc in Bioinformatics and Artificial Intelligence from Brunel University. Kanza also works on several semantic web projects across different domains such as drug discovery, agriculture and the social sciences.

Laboratories 130

Laboratories Drugs Science Small Molecule 130

Drug Target Review

MAY 27, 2024

Caris Life Sciences® (Caris) has been at the forefront of precision medicine. Caris Discovery, the therapeutic research arm of Caris Life Sciences, was launched to address the paucity of novel oncology drug targets and is uniquely poised to discover first-in-class ADC targets.

Clinical Trials 59

Clinical Trials Science Molecular Biology Bioinformatics 59

Drug Discovery World

OCTOBER 26, 2023

This requirement is met by technology from Evotec, a life sciences company that continually leads the way in proteomic research; with its PanOmics approach, Evotec seamlessly combines both data generation and analysis. Specific analyses and modules can also be easily extended according to additional scientific needs.

Drugs 130

Drugs RNA Bioinformatics Disease 130

Fierce BioTech

OCTOBER 26, 2023

They turned to Oracle Cloud Infrastructure to quickly deploy, optimize, and scale a bioinformatics pipeline for predicting protein structures in drug discovery efforts, as well as accelerate the adoption of a next-generation archive storage technology.

DNA 52

DNA Bioinformatics Engineering Science 52

Drug Discovery World

MAY 1, 2024

The company also partnered with a top 20 pharma company and has been successful in identifying antibody candidates for a target of interest, with greater diversity (2.3x) and accuracy compared to alternative bioinformatics pipeline selection methods.

FDA Approval 148

FDA Approval Therapies FDA Molecular Biology 148

The Pharma Data

JANUARY 21, 2021

NASDAQ: REGN) and Society for Science (the Society) today named 40 finalists in the Regeneron Science Talent Search 2021, the nation’s oldest and most prestigious science and math competition for high school seniors. ” Regeneron Science Talent Search 2021 Fast Facts. Regeneron Pharmaceuticals, Inc.

Science 40

Science Engineering Molecular Biology Bioinformatics 40

Drug Discovery World

JULY 11, 2023

Tim Lowery , President, JSR Life Sciences, asks whether artificial intelligence can do for life sciences what it has done in other sectors and whether these tools can keep up with the complexities of human biology. So, where do we go from here to realise their potential in life sciences?

Science 100

Science Drugs FDA Engineering 100

Drug Discovery World

APRIL 6, 2023

Science ↔ Survivor Program As mentioned previously, AACR has a Scientist↔Survivor Program. These topics will be represented across a range of session types, including methods workshops, minisymposia, poster and plenary sessions, as well as keynotes, awards and lectures.

Small Molecule 130

Small Molecule Targeted Protein Degradation Clinical Trials Engineering 130

Drug Target Review

MAY 24, 2024

5 Several major technology areas are not included above, such as cheminformatics and bioinformatics. His passion is to help early to mid-stage life sciences companies achieve novel biological breakthroughs through the effective use of computational modelling.

RNA 59

RNA DNA Bioinformatics Science 59

Drug Discovery World

OCTOBER 7, 2022

Lead author Dr Sheeba Irshad, Cancer Research UK Clinician Scientist from The School of Cancer & Pharmaceutical Sciences at King’s College London, said: “Chemotherapy resistance in aggressive early breast cancers is a major reason why cancer regrows after treatment, contributing significantly to people not surviving their disease.

Research 130

Research Immune Response Bioinformatics Treatment 130

Drug Target Review

JULY 12, 2023

Using our bioinformatics expertise, we then map those profiles onto a large database of patient data – the AACR Project GENIE database – to translationally predict which tumour types are likely to be most responsive to monotherapy or combination therapy to our drug candidate.

Biochemical Assays 98

Biochemical Assays Treatment Bioinformatics Disease 98

Drug Discovery World

DECEMBER 26, 2023

The Chan Lab at UT Southwestern will enhance PhenoScope’s tumour bank with spatial transcriptomic data and provide bioinformatic analytic expertise. SimBioSys and UT Southwestern TechBio company SimBioSys has announced a collaboration with UT Southwestern to develop cancer biomarkers for immunotherapy.

Small Molecule 130

Small Molecule Drugs Molecular Biology Bioinformatics 130

Drug Target Review

MARCH 19, 2024

He is the head of the Precision Medicine Laboratory in the School of Biomedical Sciences and Pharmacy, which comprises a team of postdoctoral fellows, research assistants, bioinformaticians and research higher degree students. Murray is also leading the HMRI Precision Medicine Research Program and is the CEO of PolygenRx.

Laboratories 105

Laboratories Bioinformatics International Research Laboratories 105

Drug Target Review

JULY 24, 2023

The results were published in Proceedings of National Academy of Sciences of United States of America (PNAS). The first identification was based on a bioinformatic analysis. Author Bio: Kan Tanaka Kan Tanaka, PhD has worked as Professor, Laboratory for Chemistry and Life Science at the Tokyo Institute of Technology since 2016.

RNA 98

RNA Regulations Bioinformatics Laboratories 98

Drug Discovery World

MAY 23, 2024

The CAS BioFinder Discovery Platform taps into science content through the CAS Content Collection, which includes the world’s most comprehensive, human-curated scientific data.

Drugs 148

Drugs Science Research Disease 148

Drug Target Review

MARCH 28, 2024

About the authors August Allen August has a decade of experience building high throughput automation, scaling teams, and solving problems at the intersection of technology and life sciences. Erica Forsberg Dr Forsberg manages the metabolomics business for Bruker Life Sciences Mass Spectrometry.

Production 128

Production Drugs Small Molecule Bioinformatics 128

Drug Discovery World

APRIL 14, 2023

Carolyn R Bertozzi, PhD – Outstanding Achievement in Chemistry in Cancer Research Bertozzi is the Baker Family Director of Sarafan ChEM-H, the Anne T and Robert M Bass Professor in the School of Humanities and Sciences, Professor of Chemistry and, by courtesy, of Chemical and Systems Biology and of Radiology at Stanford University.

Clinical Trials 130

Clinical Trials Research Science Clinical Research 130

Drug Discovery World

JULY 19, 2023

Bioinformatics and genetic sequencing are starting to be placed front and centre of public research programmes as scientists from around the world recognise the substantial benefits of knowledge sharing and resource pooling when it comes to genetic science. What does open science look like?

Science 130

Science Bioinformatics Disease Pharma Companies 130

The Open Targets Blog

AUGUST 7, 2023

Following my interest in natural sciences, I moved to Novosibirsk (central Siberia) as soon as I was able, to study general biology, with a focus on statistical genetics and bioinformatics. I am excited about the opportunity Open Targets offers to interact with science outside of academia.

Bioinformatics 52

Bioinformatics Disease Science 52

Broad Institute

AUGUST 29, 2016

The Broad Institute is pioneering a new model of collaborative biomedical science to transform biology and medicine. Computational Biology Broad computational biologists and bioinformatics analysts collaborate with interdisciplinary teams of scientists who are working together to revolutionize the way biomedical research is done.

Bioinformatics 52

Bioinformatics Engineering Science Research 52

The Pharma Data

MARCH 2, 2021

We realize more scientific opportunities by embracing the power of partnership and diversity of experts across the life-science community. Our significant investment of almost 3.5 billion euros in R&D drives innovation, enabling the next generation of medicines that save lives and improve quality of life.

Treatment 52

Treatment Bioinformatics Clinical Development Therapies 52

Drug Discovery World

OCTOBER 25, 2023

RA: How accessible have NGS technologies become for life sciences researchers? DG : With the expansion of commercial providers, literally all life science researchers now have easy access to NGS. RA: How important are bioinformatics and data analysis in helping teams analyse sequencing data?

Bioinformatics 288

Bioinformatics Pharmacogenetics RNA Medical Schools 288