Drug Target Review

MARCH 28, 2024

Between 2000 and 2020, approximately 30 percent of the newly introduced small molecule drugs were derived from natural products. About the authors August Allen August has a decade of experience building high throughput automation, scaling teams, and solving problems at the intersection of technology and life sciences.

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Production Drugs Small Molecule Bioinformatics 128

Drug Target Review

JULY 12, 2023

Once a new drug target is identified, a proprietary deep learning artificial intelligence (AI) platform we call Fluency can rapidly identify small molecules that selectively bind to a target of interest. Our assays and bioinformatics modelling can help identify certain indications that are appropriate for DCI while ruling others out.

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Biochemical Assays Treatment Bioinformatics Disease 98

The Pharma Data

NOVEMBER 15, 2020

R&D collaboration building on Lead Pharma’s expertise in the discovery, design and optimization of small molecule treatments. Lead Pharma is headquartered at Pivot Park, the biopharmaceutical life sciences campus in Oss, the Netherlands. OSS, Netherlands , Nov. OSS, Netherlands , Nov.

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Small Molecule Licensing Licensing Disease 52

Drug Discovery World

APRIL 29, 2024

Dr Andrew Lewis, Chief Scientific Officer; Kieron Hall, Chief Marketing Officer; and Eric Bironneau, Chief Business Officer, Quotient Sciences: Lewis has held various scientific leadership positions at Quotient and was previously Director of Novel Drug Delivery Technologies at Ipsen.

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Drugs Small Molecule Bioinformatics Pharmaceuticals 130

Drug Discovery World

AUGUST 7, 2024

As co-founders of Benchling, a technology company focused on life science R&D, we’ve been giving this issue a lot of thought. Companies are already starting to collaborate on open-source software projects around managing data in areas like molecular modelling, connectivity to lab instruments, and bioinformatics code.

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Pharma R&D Clinical Trials Pharma Companies Trials 173

Nvidia Developer: Drug Discovery

DECEMBER 19, 2023

The applications of artificial intelligence for enzyme generation is an exciting field of research with direct applications in the life sciences. Advances in these scientific challenges are a critical necessity to further advance drug discovery, environmental science, and bioengineering.

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Science Small Molecule Bioinformatics Research 131

Drug Discovery World

NOVEMBER 13, 2023

Thereafter, the following presentations will take place: Melody Shahsavarian, PhD, Digital Biologics Platform, Large Molecules Research, Sanofi, on: ‘Enhancing antibody discovery with generative AI’. Hiroki Shirai, PhD, Coordinator, RIKEN Center for Computational Science, on: ‘Applying deep learning anomaly detection to antibody structures’.

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Engineering Science Bioinformatics Vaccine 147

Dark Matter Blog

AUGUST 31, 2020

The majority of small molecule drugs induce their therapeutic effects by seeking out and binding to their intended target while avoiding most other molecules in the dense milieu of the cell interior. Our overall mission at Arrakis is to expand the set of “druggable” targets for small-molecule medicines to include RNA.

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RNA Small Molecule Bioinformatics Computational Chemistry 52

Elrig

APRIL 29, 2024

With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. Rising from Research Scientist to Senior Scientist, I supported early-stage DD efforts within their Protein Science group, based in Cambridge, UK.

Bioinformatics 59

Bioinformatics Molecular Biology Drugs Cell Based Assays 59

Practical Cheminformatics

JANUARY 8, 2024

A preprint from Microsoft AI Research provided a broad catalog of potential LLM applications in the physical and life sciences. Ren and coworkers from the Chinese Academy of Sciences published a preprint with one approach to overcoming some limitations of scoring structure-based generative models.

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Drugs Small Molecule Packaging Bioinformatics 141

Drug Discovery World

NOVEMBER 15, 2022

The brainchild of multidisciplinary experts in computer science, physics, engineering, and biology, the field of synthetic biology has not only rapidly progressed in the last few decades but it’s also becoming more accessible and cost-effective. “We The results of the study appeared in Science Translational Medicine earlier this year 2. .

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DNA Engineering Drugs Vaccine 246

The Pharma Data

JANUARY 10, 2021

NantWorks and ImmunityBio Chief Executive Officer, Patrick Soon-Shiong , believes that science has reached the point where it is ready to pit a “triangle offense” against even the toughest cancers. A Whole New ‘Science Matters’ Perspective . “I And then, always, ‘science matters.’ Read on for more. .

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Vaccine Regulations Disease Small Molecule 52

Codon

APRIL 16, 2023

BMC Bioinformatics. Read Basic Science *Noncoding translation mitigation. Science Advances. Read Open science and data sharing in cognitive neuroscience with MouseBytes and MouseBytes+. Science Advances. Science Translational Medicine. Read ICOR: improving codon optimization with recurrent neural networks.

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Engineering DNA RNA Science 52