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Advancing vaccine design: potential of peptide mimicry

Drug Target Review

In a new development, a recent paper published in Biology Methods & Protocols by Oxford University Press has highlighted a promising avenue for enhancing vaccine efficacy against infectious pathogens like the COVID-19 virus. The implications of this finding are far-reaching, as it holds the potential to revolutionize vaccine design.

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A chance to design better vaccines?

SCIENMAG: Medicine & Health

A new paper in Biology Methods & Protocols, published by Oxford University Press, shows it may be possible to design vaccines that will induce a stronger immune response to infecting pathogens, such as the virus causing COVID-19.

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A quiet revolution in the world of proteomics

DrugBaron

It incorporates a number of different technological advances both in the practical LC-MS data collection and in the subsequent bioinformatic analysis developed by Methuselah Health over the last decade. This can be useful to quantify protein adducts (for example when radiolabelling a protein or preparing antigens for vaccine production).

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Unlocking the potential of smart antibodies

Drug Target Review

Yanay is also the co-founder and chief scientific officer of Aulos, an immuno-oncology company working to revolutionise cancer care through the development of best-in-class IL-2 therapeutics, and co-founder and chairman of Ukko, a biotech company that designs and develops mRNA vaccines for the treatment of food allergies.

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Not all neoantigens are created equal

Drug Target Review

Recent advances in bioinformatics show clonal neoantigens are the best targets for immunotherapy, as I will elucidate below. Using powerful bioinformatics technology developed and validated with sequence data from the TRACERx study, researchers are able to identify clonal neoantigens from a patient’s unique tumour profile.

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Six scientists named as new core institute members at Broad

Broad Institute

At the Broad, he directs the Cancer Genome Computational Analysis Group , and he is a professor of pathology at Harvard Medical School and director of bioinformatics at Massachusetts General Hospital. Gad Getz is one of the world’s leaders in cancer genomics and has pioneered widely used tools for analyzing cancer genomes.

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In Silico Modeling Unveils a New Era in Rare Disease Drug Development

The Premier Consulting Blog

The information gleaned from these in silico models was used to design and test medicines against the virus, speed-up the vaccine discovery pipeline, predict any therapeutic failures, and minimize undesired effects. BMC Bioinformatics 2020, 21(Suppl 17):527 [link] Accessed April 4, 2023, at: [link] [2] Russo et al.