Biophysical Assays, Cell Biology and FDA Approval

Obstacles and innovations of macrocyclic drug development

Drug Target Review

JANUARY 16, 2025

Macrocycles, by contrast, have a higher degree of cell permeability and are also capable of binding to protein surface sites due to their size and flexibility. 6 Among the well-known FDA-approved macrocyclic drugs are those that treat Hepatitis C, a disease with previously limited therapeutic options.

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Drug Development Small Molecule Drugs FDA Approval

Drug Discovery Digest

Obstacles and innovations of macrocyclic drug development

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