Biophysical Assays, Disease and Regulations

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Biophysical Assays

Disease

Regulations

Site-Specific Molecular Glues for the 14-3-3/Tau pS214 ProteinProtein Interaction via Reversible Covalent Imine Tethering

Covalent Modifiers

FEBRUARY 10, 2025

DOI Ansgar Oberheide, Maxime van den Oetelaar, Jakob Scheele, Jan Borggrfe, Semmy Engelen, Michael Sattler, Christian Ottmann, Peter Cossar and Luc Brunsveld RSC Med Chem 2025 [link] Protein-protein interactions (PPIs) are key regulators of various cellular processes.

Biophysical Assays

Biophysical Assays Small Molecule Engineering Regulations

Advancements in hit identification for membrane protein drug discovery

Drug Target Review

APRIL 7, 2025

The challenge of GPCR drug discovery G protein-coupled receptors (GPCRs) are one of the most desirable and challenging target classes in drug discovery, as their mutation can lead to a wide range of diseases such as cancer, cardiovascular disorders and neurological conditions.

Fragment Screening

Fragment Screening Drugs Small Molecule Biophysical Assays

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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Drug Discovery Digest

Site-Specific Molecular Glues for the 14-3-3/Tau pS214 ProteinProtein Interaction via Reversible Covalent Imine Tethering

Advancements in hit identification for membrane protein drug discovery

Webinars

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