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Remove Biophysical Assays Remove Drug Development Remove Small Molecule
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Location-agnostic site-specific protein bioconjugation via Baylis Hillman adducts

Covalent Modifiers

FEBRUARY 1, 2024

link] Proteins labelled site-specifically with small molecules are valuable assets for chemical biology and drug development. Nat Commun 15 , 859 (2024). In addition to protein bioconjugation, the bis-heterocyclic scaffold we report herein will find applications in synthetic and medicinal chemistry.

Biophysical Assays 79
Biophysical Assays Small Molecule Drug Development Production 79
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Target-directed cancer: protein-ligand interactions  

Drug Target Review

NOVEMBER 1, 2023

I work in the Centre for Cancer Drug Discovery (CCDD) at The Institute of Cancer Research in London, which is an academic drug discovery centre. The mission of the CCDD is to discover novel small-molecule therapeutics for the treatment of cancer and progress them to hypothesis testing phase 1 clinical trials.

Fragment Screening 96
Fragment Screening Biochemical Assays Small Molecule Biophysical Assays 96
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