Biophysical Assays, Pharmaceuticals and Screening Hits

Biophysics

Sygnature Discovery

JUNE 17, 2024

From hit finding and target engagement studies, to the characterisation of kinetic properties for late-stage candidate molecules, we believe that a biophysical approach complements other assays to deliver a fuller picture of binding behaviour to produce more effective therapeutics.

Biophysical Assays

Biophysical Assays Screening Hits Assay Development Fragment Screening

Target-directed cancer: protein-ligand interactions

Drug Target Review

NOVEMBER 1, 2023

So that is a wide range of techniques to look at the protein-ligand interactions, all with the aim to guide the optimisation of our first screening hits to potent inhibitors that hopefully are cell-active at some point.

Fragment Screening

Fragment Screening Biochemical Assays Small Molecule Biophysical Assays

Drug Discovery Digest

Biophysics

Target-directed cancer: protein-ligand interactions

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