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Expanding Your Assay Specificity: Cisbio Joins PerkinElmer

PerkinElmer

Following the announcement that PerkinElmer has acquired Cisbio Bioassays , here is a little more information about the exciting opportunities this brings to life sciences researchers. The company notably developed a proprietary HTRF ® technology which is a type of TR-FRET assay used in Life Sciences. Learn more about Cisbio here.

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Atherosclerotic vascular disease | BMG LABTECH

BMG Labtech

Microplate readers are useful tools for researchers to investigate the many facets of cardiovascular disease and provide different options for high-throughput research of atherosclerotic vascular disease. Researchers are interested in understanding the mechanisms of disease to facilitate possible interventions.

Disease 52
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Use of Ultra-High-Throughput Screening in Discovery of COVID-19 Virus Structure

PerkinElmer

For this reason, researchers around the globe are scrambling to understand this novel virus and figure out its potentially targetable vulnerabilities. Speed is of critical importance to ongoing research efforts, given the virus’ rapid spread combined with a massive worldwide shortage of appropriate ventilator equipment.

Virus 52
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On the misuse of chemical probes

Molecular Design

It’s now time to get back to chemical probes and I’ll be taking a look at S2023 (Systematic literature review reveals suboptimal use of chemical probes in cell-based biomedical research) which has already been reviewed in blog posts from Practical Fragments , In The Pipeline and the Institute of Cancer Research.

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Assays for the Future of Drug Discovery

PerkinElmer

Successful researchers and companies master and use different technologies, making sure the interpretation of data does not suffer experimental or analytical bias and leads to better success rates and higher profitability for drug developers. The post Assays for the Future of Drug Discovery first appeared on PerkinElmer Blog.

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Separating the Hype from the Hyperbole Surrounding FDORA’s Alternatives to Animal Testing under the FD&C Act

FDA Law Blog: Drug Discovery

The definition goes on to list potential options for such tests: cell-based assays, organ chips and microphysiological systems, computer modeling, other nonhuman or human biology-based test methods such as bioprinting, as well as animal tests. FDORA § 3209(a)(2).

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Chemical con artists foil drug discovery

Molecular Design

The effects of curcumin, EGCG (epigallocatechin gallate), genistein and resveratrol on four membrane proteins were reported in Ref9 and these effects would raise doubts about activity for any of these compounds (or their close structural analogs) that had been observed in a cell-based assay.

Drugs 96