Dark Matter Blog

JULY 16, 2021

The only subject in school that held my interest was biology. As soon as I learned about DNA and RNA, I wanted to be a molecular biologist. I wanted to use molecular biology to create drugs. Last stops at RNA My last roles in biotech were where my original passion began: DNA and RNA.

Small Molecule 52

Small Molecule RNA Clinical Trials DNA 52

LifeSciVC

JULY 1, 2024

The central dogma of molecular biology is that information generally (with few exceptions) flows from DNA to RNA to Protein. In my own career, starting to write a blog was one of my most impactful “Friday afternoon experiments” – I even called it an experiment in my very first blogpost back in March 2011.

Science 86

Science Immune Response Molecular Biology RNA 86

Codon

JULY 27, 2023

.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecular biology and biophysics. How do transcription factors couple up with the correct RNA molecule?

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JULY 27, 2023

.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecular biology and biophysics. How do transcription factors couple up with the correct RNA molecule?

Therapies 52

Therapies RNA DNA Engineering 52

Codon

JUNE 26, 2023

I pulled them from a 2011 blog post ( oH mY goD tHat’S nOt pEEr-ReVieWeD!!! ) ” A blog post for the American Society for Microbiology : Early studies were promising, though experiments were often improperly designed by today's standards (i.e., Biology operates on extreme scales. A protein rotates at 60 million RPM.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

JUNE 26, 2023

I pulled them from a 2011 blog post ( oH mY goD tHat’S nOt pEEr-ReVieWeD!!! ) ” A blog post for the American Society for Microbiology : Early studies were promising, though experiments were often improperly designed by today's standards (i.e., Biology operates on extreme scales. A protein rotates at 60 million RPM.

DNA 52

DNA Therapies Engineering Clinical Trials 52

Codon

JULY 11, 2023

All cells make proteins in two steps: DNA is transcribed into messenger RNA, which is then translated into protein. It is the untouchable foundation of molecular biology. The ribosome is a molecular printer that threads ‘beads’ onto a protein string. This is simple. And we want to subvert this.

RNA 72

RNA DNA Engineering Laboratories 72