The Open Targets Blog

SEPTEMBER 21, 2023

This involves scaling up the process of making a few grams of the compound in the lab to hundreds of tonnes in a factory, in an environmentally-friendly, cost-effective way. Process chemistry is incredibly multidisciplinary: in addition to chemists, you need analytical teams to make sure everything is 99.9%

Organic Chemistry 82

Organic Chemistry Process Chemistry Small Molecule Science 82

Metabolite Tales Blog

JULY 5, 2023

Journal of Medicinal Chemistry 62 (21), 9418-9437. link] [4] Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry. link] Take a look at our other blogs The post Metabolism of macrocyclic drugs appeared first on Hypha Discovery. Balazs et al., Drug Hunter article, June 2023.

Drugs 52

Drugs Metabolic Stability FDA Approval Treatment 52

Metabolite Tales Blog

JULY 5, 2023

Journal of Medicinal Chemistry 62 (21), 9418-9437. link] [4] Macrocyclization via Ring-Closing Metathesis in Drug Discovery & Process Chemistry. link] Take a look at our other blogs The post Metabolism of de novo designed macrocyclic drugs appeared first on Hypha Discovery. Balazs et al., 20 (March 20, 2014).

Metabolic Stability 52

Metabolic Stability Drugs FDA Approval Treatment 52