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A Look Back

Dark Matter Blog

As soon as I learned about DNA and RNA, I wanted to be a molecular biologist. Last stops at RNA My last roles in biotech were where my original passion began: DNA and RNA. My last stop at Arrakis Therapeutics is with a company targeting RNA with small molecules. I wanted to use molecular biology to create drugs.

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Cave Coronavirus in Wuhan Lab Seeded COVID – The Truth Has Always Been Out There, in the Genetics

PLOS: DNA Science

The most compelling evidence for the origin lies in the RNA genome sequence similarities between RaTG13 and SARS-CoV-2 – specifically, a part that encodes the “furin binding site” of the spike protein with which the virus adheres to host cells. ” So ended my 2021 blog post a month later. Coincidence?

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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

The researchers first compared the editing efficiency of different versions of IscB when coupled with 'ωRNA,' which guides the enzyme to the right spot on the DNA. A particular variant, named IscB*-ωRNA*, had the highest editing efficiency across multiple different sites in the genome. Read more in Nature Methods.

DNA 52
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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

The researchers first compared the editing efficiency of different versions of IscB when coupled with 'ωRNA,' which guides the enzyme to the right spot on the DNA. A particular variant, named IscB*-ωRNA*, had the highest editing efficiency across multiple different sites in the genome. Read more in Nature Methods.

DNA 52
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The Codon Guide to Synthetic Biology

Codon

Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Link The coming of age of de novo protein design , by Huang P-S. Link Highly accurate protein structure prediction with AlphaFold , by Jumper J. Link ( See the blog by Mohammed AlQuraishi.) & Charpentier E.

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The Codon Guide to Synthetic Biology

Codon

Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Link The coming of age of de novo protein design , by Huang P-S. Link Highly accurate protein structure prediction with AlphaFold , by Jumper J. Link ( See the blog by Mohammed AlQuraishi.) & Charpentier E.

DNA 52