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Kickstarting the use of AI for biotechs: part two

Drug Target Review

2 AlphaFold 3 has been built to model DNA, RNA and smaller molecules (ligands). Google DeepMind’s new AI can model DNA, RNA, and ‘all life’s molecules’. He has published several papers and two books and has twelve issued patents. There are several technologies and specific tools being rolled out in this area.

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Biology is a Burrito

Codon

1 One rarely pauses to ponder how so much DNA — let alone sugar, proteins, and everything else — can fit inside such a small vessel. The graphic is from Ron Milo and Rob Phillips ’ book, Cell Biology by the Numbers , but the calculations originally appeared in the textbook, “ Physiology of the Bacterial Cell.”

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A Protein Printer

Codon

That’s because proteins are made, in the laboratory, using synthetic DNA and cells; and DNA is expensive. Our machine would make proteins without using any DNA or cells. All cells make proteins in two steps: DNA is transcribed into messenger RNA, which is then translated into protein.

RNA 64
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A Protein Printer

Codon

That’s because proteins are made, in the laboratory, using synthetic DNA and cells; and DNA is expensive. Our machine would make proteins without using any DNA or cells. All cells make proteins in two steps: DNA is transcribed into messenger RNA, which is then translated into protein.

RNA 52
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Codon Digest: Seeing Colors After Gene Therapy

Codon

They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. And that’s how I learned that there are published books that contain entire chromosome sequences. A real book that contains the full sequence of human chromosome 21.

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Codon Digest: Seeing Colors After Gene Therapy

Codon

They’ve just finished sequencing the patient’s genome, but they don’t have “DNA sorting” software. And that’s how I learned that there are published books that contain entire chromosome sequences. A real book that contains the full sequence of human chromosome 21.

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Bioprospecting in Dental Tartar from Neanderthals for Novel Antibiotics and Revisiting the Discovery of Penicillin

PLOS: DNA Science

Over time, the mineralized microbes of tooth tartar come to comprise a mouthful of tiny fossils, including snippets of degraded bacterial DNA. ” But long DNA molecules fray as they’re copied as bacteria reproduce, from ancient times leaving pieces too small to match entries in DNA databases from modern species.

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