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Scientific workflow for hypothesis testing in drug discovery: Part 1

Drug Target Review

This includes verifying the experimental design and understanding how the data was generated whether it was from RNA sequencing, mass spectrometry, or other biological assays. He has published several papers and two books and has twelve issued patents. Raminderpal earned his PhD in semiconductor modelling in 1997.

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Kickstarting the use of AI for biotechs: part two

Drug Target Review

2 AlphaFold 3 has been built to model DNA, RNA and smaller molecules (ligands). Google DeepMind’s new AI can model DNA, RNA, and ‘all life’s molecules’. He has published several papers and two books and has twelve issued patents. There are several technologies and specific tools being rolled out in this area. Alphafold 3.0:

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Fast Biology

Codon

I first encountered Von Baer’s thought experiment in Richard Fisher’s book, The Long View. At any given moment, thousands of messenger RNAs are being translated into proteins by ribosomes, which are protein-making machines that are, themselves, made from a mixture of proteins and RNA. This paper is one example.

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Optical density and absorbance measurements | BMG LABTECH

BMG Labtech

Absorbance measurements at this specific wavelength can be used to determine DNA or RNA concentrations quickly. the "Gold Book") (1997). the "Gold Book") (1997). Another crucial parameter is DNA purity since impurities or contaminants may affect the successful implementation of subsequent experiments using purified DNA samples.

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Biology is a Burrito

Codon

The graphic is from Ron Milo and Rob Phillips ’ book, Cell Biology by the Numbers , but the calculations originally appeared in the textbook, “ Physiology of the Bacterial Cell.” Students learn the basics through words: DNA is transcribed to RNA, which is translated into proteins. But what does this really mean?

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Synthetic Origins

Codon

I was reading a lot of molecular biology papers about different systems, especially circadian clocks, and also a book called Biological Feedback , by Thomas and D’Ari, that sketched out really simple models for different kinds of feedback circuits. The RNA Exporter also led to another application, which is related to the delivery issue.

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Codon Digest: Seeing Colors After Gene Therapy

Codon

And that’s how I learned that there are published books that contain entire chromosome sequences. A real book that contains the full sequence of human chromosome 21. “The first printout of the human genome to be presented as a series of books, displayed in the 'Medicine Now' room at the Wellcome Collection, London.