Codon

APRIL 30, 2023

Also, last week’s digest had an error: The country that approved the malaria vaccine was Ghana. Vaccines (basically little fat bubbles filled with mRNA and some dissolvable polymers) were physically printed onto microneedle patches using a robot. The patches have little spikes that help push the vaccines through the skin.

Vaccine 52

Vaccine DNA Engineering RNA 52

Codon

APRIL 30, 2023

Also, last week’s digest had an error: The country that approved the malaria vaccine was Ghana. Vaccines (basically little fat bubbles filled with mRNA and some dissolvable polymers) were physically printed onto microneedle patches using a robot. The patches have little spikes that help push the vaccines through the skin.

Vaccine 52

Vaccine DNA Engineering RNA 52

Codon

JULY 11, 2023

Scientists at the Institute for Protein Design have crafted proteins that self-assemble into nanomaterials or that can be used as vaccines for the flu and HIV. All cells make proteins in two steps: DNA is transcribed into messenger RNA, which is then translated into protein. Some catalyze reactions 30 million times per second.

RNA 64

RNA DNA Engineering Laboratories 64

Codon

JULY 11, 2023

Scientists at the Institute for Protein Design have crafted proteins that self-assemble into nanomaterials or that can be used as vaccines for the flu and HIV. All cells make proteins in two steps: DNA is transcribed into messenger RNA, which is then translated into protein. Some catalyze reactions 30 million times per second.

RNA 52

RNA DNA Engineering Laboratories 52

Codon

MAY 30, 2023

The researchers first compared the editing efficiency of different versions of IscB when coupled with 'ωRNA,' which guides the enzyme to the right spot on the DNA. A particular variant, named IscB*-ωRNA*, had the highest editing efficiency across multiple different sites in the genome. Read more in Nature Methods.

DNA 52

DNA RNA Engineering Vaccine 52

Codon

MAY 30, 2023

The researchers first compared the editing efficiency of different versions of IscB when coupled with 'ωRNA,' which guides the enzyme to the right spot on the DNA. A particular variant, named IscB*-ωRNA*, had the highest editing efficiency across multiple different sites in the genome. Read more in Nature Methods.

DNA 52

DNA RNA Engineering Vaccine 52

Codon

MARCH 12, 2023

The central dogma is often depicted as DNA→RNA→protein, but it’s much more: A biophysical marvel inside the smallest of vessels. The landmark paper enabled revolutions in insulin biomanufacturing, CAR-T therapies, and the bioproduction of most modern vaccines; in other words, much of what we take for granted today.

DNA 52

DNA Engineering Therapies RNA 52