Drug Discovery World

OCTOBER 14, 2022

Trapped ion mobility spectrometry: Improving the specificity of MALDI-MS-based HTS . The ability of MALDI-enabled TOF and QTOF systems to discriminate between analytes and sample matrix background components based on their specificity is, like other MS techniques, dependent upon the mass resolution. References . Attene-Ramos and M.

Synthetic Chemistry 130

Synthetic Chemistry Cell Based Assays Biochemical Assays Analytical Chemistry 130

Elrig

APRIL 29, 2024

Inspired by her time at GSK, Millie pursued a PhD at the University of Cambridge investigating the signalling pathways that drive cancer cell growth using in-vitro cell based assays and biochemical analysis. Driven by an interest in drug discovery Millie joined AstraZeneca after completion of her PhD at the end of 2020.

Bioinformatics 59

Bioinformatics Molecular Biology Drugs Cell Based Assays 59

Drug Discovery World

OCTOBER 20, 2022

Flow cytometry is a high- throughput, cell-based assay used to examine properties of single cells. It has been used to investigate rare cell populations, screen potential drug therapeutics, and examine sample phenotypes for diagnostic applications 2. Flow cytometry technologies. Conventional flow cytometry.

Cell Based Assays 130

Cell Based Assays Therapies Cell Biology RNA 130

BMG Labtech

MARCH 8, 2023

An active metabolism is a sign of viable cells and can be hence exploited by viability assays (fig.12) In addition, ATP is used as fuel by many luciferase-based assays.

Molecular Biology 52

Molecular Biology Production Cell Based Assays DNA 52