Re-assessing the risks of drug-induced arrhythmias during drug discovery
Drug Discovery World
AUGUST 15, 2023
Specifically, we propose the hypothesis that whole-heart pacing studies are more likely than standard reductionist methods to recapitulate the biology of cardiac therapy (or toxicity) in human patients and hence have higher predictive validity than conventional methods. Journal of Cardiovascular Pharmacology, 20: S96-105 Aktas et al.
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