Cell Based Assays Compound Screening Trials 
The ChEMBL-og
APRIL 16, 2024
The data in MOLECULE_DICTIONARY.MAX_PHASE now includes consideration of: EMA approved drugs (max_phase=4 for human drugs), USAN clinical candidate drugs (assigned as max_phase = 1 based on USAN guidance that states “Firms usually apply for a USAN when the investigational therapy is in Phase I or Phase II trials”.
Drug Discovery World
AUGUST 15, 2023
However, many other drugs exhibit a more complex multichannel pharmacology 7 , which is much harder to interpret and cannot be easily modelled by screening against a single ion channel. Figure 3: Electrograms (left panel) are recorded at increasingly short intervals between the stimuli (the ‘S1S2 interval’).
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