The ChEMBL-og

APRIL 16, 2024

New data have been included in the VERSION table to show the version applied for MeSH and EFO ontologies, the ChEMBL_Structure_Pipeline, RDKit packages, InChI, UniProtKB, Bioassay Ontology and Gene Ontology as well as the version of the ChEMBL database. University of Dundee: T. 1813 bioactivities in total have been added.

Clinical Trials 108

Clinical Trials FDA Cell Based Assays Compound Screening 108

Molecular Design

DECEMBER 31, 2023

These, their analogues and similar natural products persist in being followed up as drug leads and used as ‘positive’ controls even though their promiscuous actions are well-documented ( 8 , 9 ). Ref8 only discusses curcumin and I do not consider that the article documents the promiscuous actions of this compound.

Drugs 98

Drugs Packaging Cell Based Assays Small Molecule 98

Agency IQ

APRIL 12, 2024

Cell-based assays , while more complex to develop and use, offer another option for characterizing product activity at a slightly higher level, allowing sponsors to measure the further downstream effects of products (e.g., morphological cell changes or alterations in protein production or expression).

Production 40

Production FDA Therapies Biochemical Assays 40