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As the complexity of these therapeutics increases, so must the sophistication of the bioanalytical assays designed to either quantify them or measure their impact on the patient. Selecting the right assay depends on the specific immunomodulator and the clinical trial’s endpoints.
The pharmaceutical industry grapples with the persistent challenge of high attrition rates and escalating costs inherent in drugdevelopment. This necessitates exploring alternative strategies to expedite drug discovery and optimize resource allocation.
History behind animal testing In December 2022, the US Government approved the ground-breaking US Food and Drug Association (FDA) Modernization Act 2.0, 3 The first act was approved in 1938 in response to a drug — elixir sulphanilamide — that caused 105 deaths after researchers failed to test the antibiotic before release.
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Cell Based Assays 
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