Remove Cell Based Assays Remove FDA Approval Remove Trials
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ChEMBL 34 is out!

The ChEMBL-og

The data in MOLECULE_DICTIONARY.MAX_PHASE now includes consideration of: EMA approved drugs (max_phase=4 for human drugs), USAN clinical candidate drugs (assigned as max_phase = 1 based on USAN guidance that states “Firms usually apply for a USAN when the investigational therapy is in Phase I or Phase II trials”.

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Use of Ultra-High-Throughput Screening in Discovery of COVID-19 Virus Structure

PerkinElmer

The virus, which can cause a severe form of pneumonia and lead to acute respiratory distress, currently has no FDA-approved targeted therapeutic or vaccine. Of these 10,000 compounds, some were drugs already approved for other uses; others were drug candidates being used in clinical trials.

Virus 52
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Accelerating Drug Discovery Through Repurposing

DrugBank

Key techniques include high-throughput screening (HTS), cell-based assays, and animal models. The National Institutes of Health (NIH) Clinical Collection , a library of FDA-approved drugs, is widely used for HTS in drug repurposing initiatives.