Broad Institute

JUNE 30, 2023

LipocyteProfiler is a powerful imaging technique that generates comprehensive microscopy-based profiles of cells using multiple fluorescent dyes chosen specifically for studies of cardiometabolic biology. With high-resolution, cell-based profiling techniques, extracting a large amount of data can be done cheaply and efficiently.

Small Molecule 105

Small Molecule Cell Based Assays Disease Assay Development 105

Broad Institute

JUNE 21, 2023

The researchers also looked at the tool’s ability to detect changes in cell morphology after exposure to drugs and small molecule compounds. With high-resolution, cell-based profiling techniques, extracting large numbers of data can be done cheaply and efficiently.

Small Molecule 52

Small Molecule Cell Based Assays Medical Schools Disease 52

Molecular Design

DECEMBER 31, 2023

I have no problem whatsoever with people expressing opinions as to the suitability of compounds for screening provided that the opinions are not presented as facts. I do not consider it valid to present observations of frequent-hitter behavior as evidence that compounds are functioning as reactive chemicals in assays.]

Drugs 96

Drugs Packaging Cell Based Assays Small Molecule 96

Molecular Design

JUNE 8, 2023

My view is that the data analysis presented in L2021 has minimal relevance to drug discovery so I’ll be saying rather less about the data analysis than I’d have done had J Med Chem asked me to review the study. Let’s take a look now at how the authors of L2021 suggest their study be used.

Cell Based Assays 62

Cell Based Assays Small Molecule Drugs Marketing 62