Covalent Modifiers
FEBRUARY 25, 2024
2024 , DOI: 10.1039/D3CB00230F N6-Methyladenosine (m6A) is the most prevalent mRNA modification and is required for gene regulation in eukaryotes. Moreover, TD19 displays good anticancer efficacy in acute myeloid leukemia and glioblastoma multiforme cell lines.
ASPET
AUGUST 10, 2023
In cell-based assays, pegozafermin had a similar receptor engagement profile as native FGF21, with approximately 8-fold higher potency at FGF receptor 1 (FGFR1). These findings provide evidence that pegozafermin is a promising candidate molecule for the treatment of patients with NASH or SHTG.
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Broad Institute
JUNE 30, 2023
It then extracts features from images of stained cells and creates cellular profiles, categorizing cells based on patterns (often imperceptible to the human eye) that they share with other cells, which directly inform disease biology.
Broad Institute
JUNE 21, 2023
CellProfiler takes feature data extracted from Cell Painting-based images and creates cellular profiles, categorizing cells based on patterns (often imperceptible to the human eye) that they share with other cells.
BMG Labtech
MARCH 8, 2023
Cell metabolism and disease Metabolic perturbations and metabolic reprogramming are associated with common human diseases. In fact, metabolism should not be considered as a self-regulating entity that is independent of other biological pathways. On the contrary, cell metabolism affects or is affected by a multitude of processes.
Agency IQ
APRIL 12, 2024
BY RACHEL COE, MSC | APR 11, 2024 1:06 PM CDT Regulatory background: Product potency and assays As defined in statute , the FDA uses the term “potency” to refer to the “specific ability or capability” of a product to “effect a given result.” morphological cell changes or alterations in protein production or expression).
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