Cell Based Assays Research Small Molecule 
Broad Institute
JUNE 30, 2023
Common genetic variants associated with cardiometabolic disease can produce phenotype changes of such small effect that they can be difficult to characterize. The researchers also looked at the tool’s ability to detect changes in cellular phenotypes after exposure to drugs and small molecule compounds.
PerkinElmer
SEPTEMBER 8, 2019
Following the announcement that PerkinElmer has acquired Cisbio Bioassays , here is a little more information about the exciting opportunities this brings to life sciences researchers. The company notably developed a proprietary HTRF ® technology which is a type of TR-FRET assay used in Life Sciences. Learn more about Cisbio here.
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PerkinElmer
JANUARY 7, 2020
Successful researchers and companies master and use different technologies, making sure the interpretation of data does not suffer experimental or analytical bias and leads to better success rates and higher profitability for drug developers. In this assay, cells are incubated with the compound and heated.
Alta Sciences
SEPTEMBER 27, 2024
The growing understanding of the immune system's role in various diseases, along with advancements in drug development, have led to a natural evolution from traditional vaccines, small molecules , and cytokines , to increased targeted biologics and innovative approaches in gene therapy and vaccines. WHAT IS THE ALTASCIENTIST?
The ChEMBL-og
SEPTEMBER 1, 2021
In ChEMBL version 29, there are over 2 M bioactivity data points against fungal, bacterial or viral targets (for 460 K compounds) available for pathogen-related research. How can I find pathogen data? On the ChEMBL interface, the organism taxonomy is available as a filter that can be applied to bioactivity data.
Broad Institute
JUNE 21, 2023
Common genetic variants associated with cardiometabolic disease can produce phenotype changes of such small effect that they can be difficult to characterize. The researchers also looked at the tool’s ability to detect changes in cell morphology after exposure to drugs and small molecule compounds.
Molecular Design
DECEMBER 19, 2023
In any case, it needed to be made clear that the quality criteria proposed by the authors for covalently acting small-molecule probes only apply to probes that act irreversibly. Subscripting doesn't work well in blogger and so I'll use K.i As measurement of k.inact/K.i
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