Drug Target Review

JULY 25, 2023

The workflow, which has been termed STING-seq, integrates biobank-scale GWAS data with CRISPR and single-cell sequencing techniques, allowing for the identification of target genes associated with noncoding variants for blood traits. Dr Sanjana elaborated on the study for Drug Target Review. This is a great question.

Cell Based Assays 98

Cell Based Assays Disease Therapies Science 98

Alta Sciences

SEPTEMBER 27, 2024

As the complexity of these therapeutics increases, so must the sophistication of the bioanalytical assays designed to either quantify them or measure their impact on the patient. Multi-site trials are often needed, particularly for targeted therapies with strict patient criteria.

Clinical Trials 52

Clinical Trials Trials Pharmacokinetics Small Molecule 52

The Pharma Data

OCTOBER 15, 2020

ASLAN003 is a highly selective and potent inhibitor of human DHODH (IC 50 = 35 nM) and has been shown to be more than 30 times more potent at inhibiting the DHODH enzyme in cell free and cell-based assays than the first generation inhibitor teriflunomide. . SINGAPORE, Oct.

Pharmaceuticals 40

Pharmaceuticals Clinical Development Cell Based Assays Treatment 40