SCIENMAG: Medicine & Health

AUGUST 30, 2023

The discovery is a significant advance in cell biology, likely solves a long-standing mystery about an unusual feature of some ion channels […]

Cell Biology 83

Cell Biology Drugs Research 83

Drug Discovery World

AUGUST 11, 2023

When the researchers performed genetic screens on human melanoma cells to identify genes that contribute to ferroptosis, they found that VKORC1L1 is a potent inhibitor of ferroptosis.

Cell Biology 130

Cell Biology Drugs Regulations FDA 130

SCIENMAG: Medicine & Health

JULY 13, 2023

RESEARCH REVEALS HOW COVID-19 VIRUS INFECTS THE PLACENTA, AND HOW THIS CAN BE PREVENTED Credit: Monash University RESEARCH REVEALS HOW COVID-19 VIRUS INFECTS THE PLACENTA, AND HOW THIS CAN BE PREVENTED In a landmark study published in Nature Cell Biology, Australian researchers, led by Professor Jose Polo from Monash University and the University of (..)

Cell Biology 77

Cell Biology Virus Research 77

Chemical Biology and Drug Design

JULY 26, 2023

lncRNA, miRNA, siRNA, receptors, and proteins) are added to exosomes which are released from the parental cells. Abstract Noncoding RNAs (ncRNAs) are engaged in key cell biological and pathological events, and their expression alteration is connected to cancer progression both directly and indirectly.

Engineering 100

Engineering Therapies Cell Biology Drugs 100

Chemical Biology and Drug Design

JANUARY 5, 2024

After the corresponding transfection or treatment with inhibitor of catenin-responsive transcription-3 (iCRT-3), abovementioned CRC cell biological behaviors as well as expression levels of HOXB7 and β-catenin were evaluated. μM THA dwindled CRC cell viability, migration, and invasion, and facilitated apoptosis.

Bioinformatics 100

Bioinformatics Cell Biology Treatment Research 100

Drug Target Review

JULY 13, 2023

The aim is to establish condensate biology as a fundamental branch of cell biology – “cell biology 2.0” The underlying biology and processes upon which the company was founded have broad applicability across various human disease areas. Klein notes the importance of Dewpoint’s disease-agnostic approach.

Disease 98

Disease Small Molecule Cell Biology Medical Schools 98

Drug Discovery World

APRIL 5, 2023

Members contribute their expertise in high throughput screening, structural biology, medicinal chemistry, compound profiling, cancer cell biology, and in vivo and in vitro models for oncology.

Small Molecule 130

Small Molecule Cell Biology Laboratories Engineering 130

Drug Discovery World

JULY 11, 2023

The funding will support preclinical development, including development of a manufacturing process in collaboration with the Cell and Gene Therapy Catapult, whose mission is to support the UK’s cell and gene therapy industry.

Therapies 100

Therapies Cell Biology Engineering Production 100

Drug Discovery World

SEPTEMBER 2, 2022

Read the original paper: ‘Eps15/Pan1p is a master regulator of the late stages of the endocytic pathway’ in the Journal of Cell Biology. It also has a crucial role in actin polymerisation and drives the recruitment of a range of actin nucleation promoting factors.

Cell Biology 130

Cell Biology Science Regulations Therapies 130

Chemical Biology and Drug Design

JULY 27, 2023

DDP-resistant NPC cells were established by treatment with DDP at increased concentrations (2, 4, 6, 8, or 10 μg/mL). Cell biological behaviors were assessed via cell function experiments. MicroRNA-577 and EIF5A2 mRNA expressions were detected by qRT-PCR.

Regulations 100

Regulations Cell Biology Treatment Research 100

Drug Discovery World

AUGUST 11, 2022

The partnership will combine MDC’s expertise in cell biology and drug discovery with ZEISS’ microscope instrumentation and image analysis capabilities. A new partnership has been formed between Medicines Discovery Catapult (MDC) and technology group ZEISS to improve drug discovery using advanced microscopy solutions. .

Cell Biology 130

Cell Biology Drugs Laboratories Disease 130

KIF1A

MARCH 2, 2024

Read the Article Rare Roundup The Jackson Laboratory offers “Exploring Rare Disease Through Translational Research” MiniCourse Human health is incredibly complex; developing safe, effective treatments requires knowledge of molecular mechanisms, cell biology, and drug administration.

Laboratories 119

Laboratories Cell Biology Disease Research 119

Broad Institute

DECEMBER 13, 2023

Hacohen Group, Cell Circuits Bhaavana Oruganty Swarthmore College Engineering (major), B.S., Chemistry (minor) Golub Lab, Cancer Program Ava Perry Texas A&M University Molecular and Cell Biology (major), B.S., Biochemistry (minor) Golub Lab, Cancer Program Alexander Rojas Emory University Biology B.S.

Molecular Biology 52

Molecular Biology Cell Biology Engineering Science 52

Drug Discovery World

APRIL 18, 2023

Riccardo Dalla-Favera, a Fellow of the AACR Academy, is Director of the Institute for Cancer Genetics; the Percy and Joanne Uris Professor of Clinical Medicine; Professor of Pathology and Cell Biology, Microbiology and Immunology, and Genetics and Development; and member of the Herbert Irving Comprehensive Cancer Center at Columbia University.

DNA 130

DNA Bioinformatics Cell Biology Clinical Trials 130

Drug Target Review

OCTOBER 16, 2023

Nikki drives adoption of 3D cellular models of human disease by applying her expertise in cell biology to drug discovery and high-throughput screening. About the author Nikki Carter Commercial Organoid Innovation Director, Molecular Devices. Nikki’s life sciences experience spans leadership, commercial and research roles.

Disease 121

Disease Immune Response Cell Biology Engineering 121

Drug Discovery World

JANUARY 26, 2023

Senior author Marcia Haigis, Professor of cell biology in the Blavatnik Institute at Harvard Medical School has been working in this area for 15 years. With further research, the team at Harvard Medical School hope that more targeted therapies can be developed to treat cancers whose growth is fuelled by this metabolite.

Medical Schools 130

Medical Schools Cell Biology Research Therapies 130

Drug Target Review

NOVEMBER 24, 2023

Achieving a mouse brain map has been made possible by advances in computing and data processing, as well as previous work by Lichtman and other researchers like Professor Florian Engert in molecular and cell biology, studying the brains of fruit flies and zebrafish.

Cell Biology 104

Cell Biology Engineering Research Treatment 104

The Pharma Data

OCTOBER 27, 2021

million expansion will bring high quality seeds to worldwide markets faster, providing solutions for growers and meeting consumer demands / The seven-hectare global Product Design Center in San Nicolás includes state-of-the-art lab space for cell biology research and greenhouses for seed production.

Cell Biology 40

Cell Biology Production Laboratories Marketing 40

Drug Discovery World

AUGUST 17, 2023

DDW Volume 24 – Issue 3, Summer 2023 Biography: Alok Javali gained his PhD from the Institute of Stem Cell Biology and Regenerative Medicine. He joined Nicolas Rvron’s lab in 2020, where he co-invented human blastoids; the model of early human embryos derived solely from stem cells.

Cell Biology 130

Cell Biology International Science Drug Development 130

Drug Target Review

AUGUST 10, 2023

When bound to GRP78, ID2 loses its inhibitory function, leading to increased invasiveness of cancer cells. Implications for cancer therapeutics and beyond These findings have wide-ranging implications for cancer treatment and cell biology research.

Cell Biology 52

Cell Biology Small Molecule Regulations Engineering 52

The Pharma Data

MARCH 16, 2022

The research scientist at the Max Planck Institute for Medical Research received the award in recognition of his ground-breaking work in establishing various approaches to protein labeling in living cells that have enabled far-reaching advances in chemical and cell biology. Protein labeling (e.g.

Molecular Biology 52

Molecular Biology Cell Biology Science Laboratories 52

Drug Discovery World

AUGUST 10, 2023

DDW Volume 24 – Issue 3, Summer 2023 Biography: Neil Dhawan is the Co-founder and CEO of Totus Medicines, where he focuses on combining small molecule design, structural biology, genetics, biochemistry, and cell biology to design new classes of drugs to target untreatable diseases.

Small Molecule 130

Small Molecule Clinical Trials Cell Biology Disease 130

Drug Target Review

JUNE 7, 2024

She has deep knowledge in Immunology and T cell biology, and 13 years of experience in Research (seven of them in biotech at Immunocore), including pipeline programme leadership. Dr Ribeiro holds a PhD in Biomedical Sciences from University of Porto, Portugal, studying T cell and thymus development.

Engineering 81

Engineering Clinical Trials Therapies Cell Biology 81

Drug Discovery World

OCTOBER 18, 2023

in Cell Biology and Biochemistry from University College London and was a post-doctoral fellow at Albert Einstein College of Medicine in New York City. She received a Ph.D. References 1: U.S. Food & Drug Administration (2017) FDA approves novel gene therapy to treat patients with a rare form of inherited vision loss.

Therapies 162

Therapies Clinical Trials FDA Approval Virus 162

Drug Target Review

APRIL 9, 2024

Initial works from the lab concentrated on exploring the role of replicative stress in cancer and ageing, for which the group combined cell biology, mouse models and drug development projects. In 2005, he joined CNIO to lead the Genomic Instability Group where he has been ever since.

RNA 63

RNA Cell Biology Clinical Development DNA 63

Drug Target Review

OCTOBER 31, 2023

When I was studying cell biology, looking at how cells divide, I couldn’t fathom how math could possibly fit into that. My undergraduate studies focused on biochemistry and cell biology, so very much STEM-based, but my professors and mentors noticed my penchant for critical thinking which led me to consider law.

Cell Biology 107

Cell Biology Pharmaceuticals Science International 107

PerkinElmer

JANUARY 21, 2022

Accelerating Capabilities for Dementia Biomarker Discovery To achieve that goal, the Dementia Platform’s focus involves studying the disease from many points of view – from lifestyle, age, and cognitive function, to genetics, cell biology, and phenotypic screening.

Cell Biology 52

Cell Biology Disease Treatment Science 52

Drug Target Review

NOVEMBER 1, 2023

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. The Journal of Cell Biology. Umezu-Goto M, Kishi Y, Taira A, et al. 2002 Jul 22;158(2):227–33. Valdés-Rives SA, González-Arenas A. Autotaxin-Lysophosphatidic Acid: From Inflammation to Cancer Development.

Clinical Trials 134

Clinical Trials Small Molecule Trials Pharmacokinetics 134

The Pharma Data

FEBRUARY 24, 2022

Their findings are published online in Nature Cell Biology. “We are amazed by the efficiency of small-molecule PROTAC in simultaneously targeting EZH2 and cMyc in cancer cells.” MS177 targets both EZH2 and cMyc and thus inhibit cancer growth.

Small Molecule 52

Small Molecule Cell Biology Research Drug Development 52

Broad Institute

MARCH 25, 2024

in cell biology. Navarro later became the first in her family to attend a four-year college, earning her degree in microbiology from the University of Texas at El Paso, followed by a stint doing research at Novartis in Cambridge, MA, and then graduate studies at MIT to earn her Ph.D.

Science 112

Science Cell Biology Research DNA 112

Precision for Medicine

APRIL 7, 2023

The custom-designed laboratory accommodates the growth in demand for advanced digital pathology and imaging capabilities, expertise in molecular sciences and a wide array of sequencing technologies.

Laboratories 52

Laboratories Clinical Research Clinical Trials Cell Biology 52

Drug Discovery World

AUGUST 5, 2022

She holds a PhD in Molecular and Cell Biology from the Faculty of Medicine, University of Auvergne and a MSci in Biochemistry from the Faculty of Sciences, University of Lisbon.

DNA 130

DNA Engineering Cell Biology Doctors 130

Drug Discovery World

APRIL 14, 2023

He is being recognised for his fundamental discoveries dedicated to characterising the genetic drivers of human B-cell lymphomas and for uncovering new avenues for cancer prevention and therapy that have been routinely exploited clinically to diagnose and determine novel therapeutic strategies for B-cell lymphoma.

Clinical Trials 130

Clinical Trials Research Science Clinical Research 130

The Pharma Data

JUNE 28, 2021

. • Addie Thompson – Michigan State University • Ana Laura Torres Huerta – Monterey Institute of Technology • Bryan Berger – University of Virginia • Eduardo Rodriguez – Institute of Molecular and Cell Biology of Rosario • Elizabeth Skellam – University of North Texas • Enrico Bonello – Ohio State University • Haoyu Niu – University of California, (..)

Research 52

Research Cell Biology Science Disease 52

The Pharma Data

MARCH 15, 2022

. “The problem is that cells only make small amounts of p53 and then quickly break it down as it is a very large and disordered protein,” says the study’s last author Michael Landreh, researcher at the Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet.

Cell Biology 52

Cell Biology DNA Research Vaccine 52

Drug Target Review

JANUARY 30, 2024

About the author Dr Jia-Jia Zhang, Doctoral candidate Dr Jia-Jia Zhang is a doctoral candidate at the National Translational Science Center for Molecular Medicine & Department of Cell Biology, Fourth Military Medical University, and her research interest is the development of therapeutical antibodies to treat human disease.

Treatment 52

Treatment Doctors Cell Biology Regulations 52

SCIENMAG: Medicine & Health

JULY 28, 2023

As life propagated across Earth in the form of the widest variety of single-celled organisms, sometime between 3.5 As a host cell, it offered […] and a billion years ago one such organism managed an evolutionary coup: Instead of devouring and digesting bacteria, it encapsulated its prey and used it as a source of energy.

Cell Biology 82

Cell Biology 82