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Cell and gene therapy development moves into cardiac indications

Drug Target Review

Cell and gene therapies (CGTs) have made significant advancements in treating oncological diseases, with therapies like CAR-T cell treatments transforming cancer care. Early-phase clinical trials have shown the safety and efficacy of using stem cells for cardiac repair, encouraging further research and development.

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How nucleolar stress accelerates aging in mice

Drug Target Review

How has nucleolar stress (NS) been linked to age-related diseases, and what approach did researchers use to investigate its toxicity? The nucleolus (and nucleolar stress) had been previously linked to aging and age-related diseases such as cancer or degeneration.

RNA 64
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#WhyIScience Q&A: A cell biologist now helps recent college graduates launch their scientific careers

Broad Institute

in cell biology. During college, I studied microbiology and developed an interest in infectious disease. In my honors biology class, I chatted with my professor about a report I wrote on cancer therapeutics. Each cell needs the same amount of DNA so they can function like each other.

Science 111
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TACACICLIB, AUR-102, AURIGENE

New Drug Approvals

The present invention is directed to methods of preparation of compound of formula (I) that is useful for inhibiting Cyclin-dependent kinase 7 (CDK7) and for treating diseases or disorders mediated thereby. Recent genetic and biochemical studies have confirmed the importance of CDK7 for cell cycle progression (Larochelle. Cancer Res.

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Codon Digest: Vaccine Printer Go Brrrrr!

Codon

2/ Live Long and Prosper, Lil’ Yeasty Boys Yeast cells usually live for about one week. Yeast die for two reasons: Either their nucleolus (where the DNA is kept) degrades and dies, or their mitochondria whimpers out and they stop making energy. kilobases” of DNA into a plant genome. (My From Zhang et al.

Vaccine 52
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Codon Digest: Vaccine Printer Go Brrrrr!

Codon

2/ Live Long and Prosper, Lil’ Yeasty Boys Yeast cells usually live for about one week. Yeast die for two reasons: Either their nucleolus (where the DNA is kept) degrades and dies, or their mitochondria whimpers out and they stop making energy. kilobases” of DNA into a plant genome. (My From Zhang et al.

Vaccine 52
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Codon Digest: Injected Gene Editors

Codon

But now, by studying DNA extracted from microbes in the blood of almost 10,000 healthy people, this paper shows that there is no such thing. Read Transcription factors bind to DNA and control gene expression. They tend to “group up” in cells. Molecular Systems Biology. Nature Microbiology. Meeussen J.V.W.

DNA 52