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How to advance AAV-based gene therapies

Drug Discovery World

Sara Donnelly, Director of Research Planning and Business Development at PhoenixBio USA explores why the right pre-clinical model is essential for teams wanting to advance adeno-associated virus vector-based gene therapies. Adeno-associated virus (AAV) vector-based gene therapies hold exceptional promise across a range of disease areas.

Therapies 162
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A research team searches for every gene that helps tumors evade immunotherapy

Broad Institute

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. His mother had a presentation of the disease that suggested her immune system was already on the job.

Research 137
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Discovering an Antimalarial Drug in Mao’s China

Codon

“Cumulatively the deadliest of the human infectious diseases,” malaria has been documented throughout recorded history. In this light, scouring old Chinese remedies for new treatments for a disease specifically troublesome during war was entirely intuitive for Chinese biomedical scientists like Tu Youyou in the mid-20th century.

Drugs 129
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AI At The Frontier: Empowering Early Career Professionals In Drug Discovery

Elrig

Co-Chair: Millie Fox Co-Chair: Millie Fox Senior Drug Discovery Scientist, AstraZeneca Millie graduated from the University of Sussex with a Biochemistry degree in 2016, which included an industrial placement year at GSK, Stevenage.

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From the Top: Adele Hannigan, Antibody Analytics

Drug Discovery World

AH : I am Chief Business Officer for Antibody Analytics, a collaborative immunology CRO, specialising in supporting immunotherapy developers at the discovery to pre-clinical stages of the drug development process. MT: Who or what inspires you? MT: What drives you professionally and personally?