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A research team searches for every gene that helps tumors evade immunotherapy

Broad Institute

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. His mother had a presentation of the disease that suggested her immune system was already on the job.

Research 137
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AI At The Frontier: Empowering Early Career Professionals In Drug Discovery

Elrig

She has played a key role inbuilding the target identification platform and a proprietary database of transcriptome-wide, functional RNA structures. Interactive Q&A session: Pose your questions directly to the experts and get tailored insights to your interests and concerns.

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What to expect from PEGS Europe 2023: Day 3

Drug Discovery World

Jens Fischer, PhD, Program Manager, Large Molecule Research Therapeutic Modalities, Roche Pharma Research and Early Development (pRED), on: ‘ Bispecific and next-generation antibodies for non-oncology indications such as ophthalmologic and neurologic diseases’.

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Flow cytometry technologies and cancer associated fibroblasts

Drug Discovery World

Inside any solid tumour there is high heterogeneity, and the types of tumour cells, immune cells, and stromal cells present and their functional states dictate disease severity and progression. Instead, fibroblasts are frequently identified using a combination of positive and negative markers along with cell morphology.