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Condensate biology: advancing drug discovery for complex diseases

Drug Target Review

In this article, we will delve into the world of condensate biology and explore the groundbreaking research projects undertaken to discover the potential they hold for diseases such as amyotrophic lateral sclerosis ( ALS ) and colorectal cancer. Klein notes the importance of Dewpoint’s disease-agnostic approach.

Disease 98
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Cancer metastasis: breakthrough in therapeutic strategies

Drug Target Review

Published in the Proceedings of the National Academy of Sciences , a new discovery from the University of Southern California (USC) on cancer metastasis has opened up new possibilities for combating the spread of this devastating disease.

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The future of mRNA biology and AI convergence

Drug Target Review

mRNA biology has become widely recognised as a new “drug mine” RNAi drugs are in the market and mRNA vaccines, initially developed for Covid-19, are already in trials for cancer. All of these are novel targets to be explored in small molecule drug discovery as well as for improving the efficacy of mRNA vaccines.

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What to expect from PEGS Europe 2023: Day 3

Drug Discovery World

Jens Fischer, PhD, Program Manager, Large Molecule Research Therapeutic Modalities, Roche Pharma Research and Early Development (pRED), on: ‘ Bispecific and next-generation antibodies for non-oncology indications such as ophthalmologic and neurologic diseases’.

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Codon Digest: Vaccine Printer Go Brrrrr!

Codon

If these printers were set up in resource-starved countries, where malaria and other diseases are endemic, they could make a world of difference. 5/ Lots O’ Gene Therapies Not one, but two applications for sickle-cell gene therapies have been submitted to the F.D.A. Nature Cell Biology. Synthetic Biology.

Vaccine 52
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Codon Digest: Vaccine Printer Go Brrrrr!

Codon

If these printers were set up in resource-starved countries, where malaria and other diseases are endemic, they could make a world of difference. 5/ Lots O’ Gene Therapies Not one, but two applications for sickle-cell gene therapies have been submitted to the F.D.A. Nature Cell Biology. Synthetic Biology.

Vaccine 52
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Codon Digest: Injected Gene Editors

Codon

An open-source FACS automation system for high-throughput cell biology. Cell Systems. Read Small-molecule aptamer for regulating RNA functions in mammalian cells and animals. Read The FDA is reviewing a “controversial cell therapy for ALS,” developed by BrainStorm Cell Therapeutics.

DNA 52