Drug Target Review

JULY 13, 2023

In this article, we will delve into the world of condensate biology and explore the groundbreaking research projects undertaken to discover the potential they hold for diseases such as amyotrophic lateral sclerosis ( ALS ) and colorectal cancer. Klein notes the importance of Dewpoint’s disease-agnostic approach.

Disease 98

Disease Small Molecule Cell Biology Drugs 98

Drug Target Review

NOVEMBER 1, 2023

2 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. 1-5 Implication of ATX in a large range of human diseases have been highlighted by both fundamental research and clinical trials. The Journal of Cell Biology. 2002 Jul 22;158(2):227–33.

Clinical Trials 134

Clinical Trials Small Molecule Trials Disease 134

Drug Target Review

AUGUST 10, 2023

Published in the Proceedings of the National Academy of Sciences , a new discovery from the University of Southern California (USC) on cancer metastasis has opened up new possibilities for combating the spread of this devastating disease.

Cell Biology 52

Cell Biology Small Molecule Regulations Engineering 52

The Pharma Data

OCTOBER 19, 2020

an emerging leader focused on the treatment of kidney disease, sepsis and organ injury, today announced the appointment of Maarten Kraan, M.D., At Aduro, he was responsible for all manufacturing and supply chain activities for the company’s biologics and small molecules and managed a transatlantic team. 20, 2020 09:00 UTC.

Trials 40

Trials Small Molecule Cell Biology Clinical Trials 40

NIH Director's Blog: Drug Discovery

APRIL 11, 2017

Credit: National Center for Advancing Translational Sciences, NIH When you think of the causes of infectious diseases, what first comes to mind are probably viruses and bacteria. Missing was the usual pocket-shaped active site, where a traditional small molecule can readily bind and block function. ” [1] Or was it?

Small Molecule 52

Small Molecule Science Drug Development Disease 52

Drug Target Review

JULY 23, 2024

Shortly after finishing my studies, I landed my first job in industry working on cell biology research for several disease indications. TPD engages the body’s natural protein recycling system by selectively eliminating disease-causing proteins, ultimately addressing the root cause of disease.

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Small Molecule Targeted Protein Degradation Science Disease 115

Drug Target Review

DECEMBER 21, 2023

All of these are novel targets to be explored in small molecule drug discovery as well as for improving the efficacy of mRNA vaccines. However, our inability to understand that biology is what stands in the way of further progress. And since mRNA biology is like the highway of cell biology, it would likely be visible there.

Disease 105

Disease Small Molecule Vaccine Drugs 105