This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cellbiology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. These cells also express the Cas9 protein, which helps disable the genes targeted by the guide RNAs.
For my PhD project, I chose an advisor who worked on DNA and I started working with her on the physical properties of DNA. I worked with Jackie Barton in the early days of what’s now called DNA-mediated electron transfer. I went to Genentech and postdoc-ed for Jim Wells in protein engineering.
My search made me appreciate how remarkable it is that life functions at all, considering the chaotic conditions in which cells exist. It also gave me a new appreciation for biology, and the incredible exactitude that one must have to engineer it — let alone engineer it successfully. of a Boeing 737 jet engine.
The heart does have limited regenerative capacity, but not enough of the healthy cells that capable of restoring function, making it difficult to recover from injuries such as myocardial infarction. However, cell-based therapies are intended to leverage those healthy cells via transplant to regenerate damaged tissue.
This is Codon Digest, a weekly roundup of research papers, news articles, and industry highlights about engineeredbiology. ” — Samuel Butler , 1878 (* = My picks) AI + Bio Characterizing the interaction conformation between T-cell receptors and epitopes with deep learning. Molecular Systems Biology.
Read more at Nature Biotechnology ( Similar paper at Nature Biomedical Engineering.) How to make a cell-penetrating Cas9 protein, and then incubate it with peptides to edit human cells. 2/ Live Long and Prosper, Lil’ Yeasty Boys Yeast cells usually live for about one week. Nature Biomedical Engineering.
Read more at Nature Biotechnology ( Similar paper at Nature Biomedical Engineering.) How to make a cell-penetrating Cas9 protein, and then incubate it with peptides to edit human cells. 2/ Live Long and Prosper, Lil’ Yeasty Boys Yeast cells usually live for about one week. Nature Biomedical Engineering.
LanzaTech announced a partnership with H&M Move to convert factory carbon emissions into fabrics using engineered microbes. Stem cells from macaques were converted into synthetic embryos, and then those embryos were implanted back into eight different female macaques. Read *Functional synthetic biology. Shrock E.L.
Srinivasan has led the development of multiple computational pipelines to process data from different next generation sequencing techniques with applications in oncology, genome editing systems including CRISPR-Cas mediated DNA editing, and ADAR-mediated RNA editing.
During this process, the cells’ genomes ditch their methyl groups, an important epigenetic mark. Erasing methyl groups on DNA is necessary for normal egg and sperm development. Reaching the oogonia stage marked an impressive achievement in germ cellbiology, because previous methods only went up to the PGC stage.
Codon Digest is my weekly roundup of research, news, and industry highlights about engineeredbiology. epidermidis , can actually trigger tumor-specific T cells. In other words: Brush some engineered bacteria on the skin, and they activate the immune system to go fight a tumor. Please send me your feedback.
For example, cloning DNA molecules and inserting them into cells — a process required for basically all experiments in molecular biology — takes up to a week of work. But looking ahead to the second bottleneck, what does it mean to say that biology is “complex”? Even the humble E.
Experiments performed with the bacterium Streptococcus pneumoniae not only led to the discovery of DNA as the principal hereditary molecule but also yielded early tools for genetic engineering. The study of RNA tumor viruses revealed reverse transcriptase , an enzyme integral in studying RNA biology.
Credit: Bruce Wetzel and Harry Schaefer, NCI, NIH | License Progress in biology is arguably moving faster today than at any point in the course of human history. Engineeredbiology has profound potential to change how we live, but the field has become broad, bloated, nebulous. Nature Reviews Molecular CellBiology (2009).
Credit: Bruce Wetzel and Harry Schaefer, NCI, NIH | License Last edit: 13 September 2023 Progress in biology is arguably moving faster today than at any point in the course of human history. Engineeredbiology has profound potential to change how we live, but the field has become broad, bloated, nebulous. Nature (2005).
We organize all of the trending information in your field so you don't have to. Join 15,000+ users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content