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A different approach: reimagining biology

Drug Discovery World

Three key members of the team – Dr Raquel Sanches-Kuiper, Vice President of Technology, Dr Matthew Hayes, Chief Technology Officer and John Edgell, Head of Cloud Engineering – explain how the company is doing this and what it means for the advancement of DNA synthesis in the lab. The next goal is to optimise the technology. “At

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Who are the AACR Scientific Achievement Award winners?

Drug Discovery World

He is being recognised for his revolutionary contributions to developing the first gene-edited cell-based therapy for cancer that involves the genetic re-engineering of a patient’s own T cells to combat their disease, and for demonstrating that adoptive T-cell therapy can induce remission and in some cases cure patients with advanced cancer.

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What to expect from PEGS Europe 2023: Day 3

Drug Discovery World

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Ali Madani, PhD, Founder and CEO, Profluent Bio, on: ‘Protein engineering with large language models’.

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Codon Digest: Vaccine Printer Go Brrrrr!

Codon

Read more at Nature Biotechnology ( Similar paper at Nature Biomedical Engineering.) How to make a cell-penetrating Cas9 protein, and then incubate it with peptides to edit human cells. 2/ Live Long and Prosper, Lil’ Yeasty Boys Yeast cells usually live for about one week. Nature Biomedical Engineering.

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Codon Digest: Vaccine Printer Go Brrrrr!

Codon

Read more at Nature Biotechnology ( Similar paper at Nature Biomedical Engineering.) How to make a cell-penetrating Cas9 protein, and then incubate it with peptides to edit human cells. 2/ Live Long and Prosper, Lil’ Yeasty Boys Yeast cells usually live for about one week. Nature Biomedical Engineering.

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Delivering on the promise of gene editing

Drug Discovery World

As gene editing technologies like CRISPR progress toward clinical study, researchers must continue to advance new approaches and address inherent challenges, explains Jon Chesnut, PhD, Senior Director, Cell Biology R&D, Thermo Fisher Scientific. Reduce/eliminate chromosomal disruptions caused by double-strand DNA breaks.

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Codon Digest: Injected Gene Editors

Codon

This is Codon Digest, a weekly roundup of research papers, news articles, and industry highlights about engineered biology. ” — Samuel Butler , 1878 (* = My picks) AI + Bio Characterizing the interaction conformation between T-cell receptors and epitopes with deep learning. Molecular Systems Biology.

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