Broad Institute

OCTOBER 11, 2023

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. They are used to treat cancers including melanoma and non-small cell lung cancer, but work only for a small fraction of patients.

Research 137

Research Immune Response Clinical Trials Cell Biology 137

Drug Discovery World

DECEMBER 15, 2022

As gene editing technologies like CRISPR progress toward clinical study, researchers must continue to advance new approaches and address inherent challenges, explains Jon Chesnut, PhD, Senior Director, Cell Biology R&D, Thermo Fisher Scientific. Reduce/eliminate chromosomal disruptions caused by double-strand DNA breaks.

DNA 130

DNA Clinical Trials Therapies RNA 130

Codon

APRIL 30, 2023

2/ Live Long and Prosper, Lil’ Yeasty Boys Yeast cells usually live for about one week. Yeast die for two reasons: Either their nucleolus (where the DNA is kept) degrades and dies, or their mitochondria whimpers out and they stop making energy. Printed vaccines caused mice to have a faster immune response.

Vaccine 52

Vaccine DNA Engineering RNA 52

Codon

APRIL 30, 2023

2/ Live Long and Prosper, Lil’ Yeasty Boys Yeast cells usually live for about one week. Yeast die for two reasons: Either their nucleolus (where the DNA is kept) degrades and dies, or their mitochondria whimpers out and they stop making energy. Printed vaccines caused mice to have a faster immune response.

Vaccine 52

Vaccine DNA Engineering RNA 52

Drug Discovery World

NOVEMBER 13, 2023

Enkelejda Miho, PhD, Professor, University of Applied Sciences and Arts Northwestern Switzerland, and Managing Director, aiNET, on: ‘The singular immune response to dengue and machine learning identification of antibodies in high-throughput sequences’.

Engineering 148

Engineering Science Bioinformatics Vaccine 148

Codon

APRIL 9, 2023

Small snippets of double-stranded RNA were sprayed onto hot pepper plants to control a pest, called Frankliniella occidentalis. The RNA strands shut down a specific gene in the insects, and killed half after 7 days. RNA may offer a safer form of pest control in the future. Nature Chemical Biology. Current Biology.

Therapies 52

Therapies RNA Engineering Vaccine 52

Codon

APRIL 16, 2023

This looks like an early step toward a much different future for biology: One in which natural language is used to design experiments, program robots, and automate experiments in high-throughput. Skin microbes can trigger strong immune responses. epidermidis , can actually trigger tumor-specific T cells. coli K12 biofilm.

Engineering 52

Engineering DNA RNA Science 52