Drug Discovery World

AUGUST 5, 2022

Three key members of the team – Dr Raquel Sanches-Kuiper, Vice President of Technology, Dr Matthew Hayes, Chief Technology Officer and John Edgell, Head of Cloud Engineering – explain how the company is doing this and what it means for the advancement of DNA synthesis in the lab. Why enzymatic synthesis? “We

DNA 130

DNA Engineering Cell Biology Doctors 130

Drug Target Review

APRIL 9, 2024

For his postdoctoral stay he joined the group of André Nussenzweig, where he started to work on DNA repair, particularly focusing on the role of histone H2AX. Today, several companies have ATR inhibitors at various stages of clinical development, which to a significant extent was influenced by early works from the laboratory.

RNA 63

RNA Cell Biology Clinical Development DNA 63

Codon

APRIL 2, 2023

But now, by studying DNA extracted from microbes in the blood of almost 10,000 healthy people, this paper shows that there is no such thing. Read Transcription factors bind to DNA and control gene expression. They tend to “group up” in cells. Molecular Systems Biology. Nature Microbiology. Meeussen J.V.W.

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DNA RNA Engineering Licensing 52

Drug Discovery World

NOVEMBER 13, 2023

Michael Traxlmayr, PhD, Group leader, CD Laboratory for Next-Generation CAR T Cells, University of Natural Resources & Life Sciences, on: ‘Novel concepts to regulate CAR T cell activity with small molecule drugs in vivo’.

Engineering 147

Engineering Science Bioinformatics Vaccine 147

BMG Labtech

MARCH 8, 2023

DNA, proteins, polysaccharides, etc.). Cells require energy for this process. 2 Organisms are categorised based on their anabolism and according to the source used by cells to build-up molecules. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press. nucleotides, monosaccharides, etc.), doi:10.1101/glycobiology.3e.005

Molecular Biology 52

Molecular Biology Production Cell Based Assays DNA 52

Drug Discovery World

OCTOBER 14, 2022

Lundblad, Drug Design, in Encyclopedia of Cell Biology (Volume 1), Elsevier, 2016. García-Riestra, Application and perspectives of MALDI–TOF mass spectrometry in clinical microbiology laboratories, Microorganisms, 2021, 9: 1539, [link]. References . Attene-Ramos and M. Elsen and J.D. Torres-Sangiao, C. Leal Rodriguez and C.

Synthetic Chemistry 130

Synthetic Chemistry Cell Based Assays Biochemical Assays Analytical Chemistry 130

Codon

APRIL 9, 2023

Marine sponges were cultured in the laboratory continuously for the first time. Sponge cells double in population quite quickly — around 40 minutes — and could be engineered to manufacture drugs. Read DNA Sequencing & Synthesis *Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing.

Therapies 52

Therapies RNA Engineering Vaccine 52