Drug Target Review

APRIL 9, 2024

For his postdoctoral stay he joined the group of André Nussenzweig, where he started to work on DNA repair, particularly focusing on the role of histone H2AX. Today, several companies have ATR inhibitors at various stages of clinical development, which to a significant extent was influenced by early works from the laboratory.

RNA 64

RNA Cell Biology Clinical Development DNA 64

Codon

APRIL 2, 2023

But now, by studying DNA extracted from microbes in the blood of almost 10,000 healthy people, this paper shows that there is no such thing. Read Transcription factors bind to DNA and control gene expression. They tend to “group up” in cells. Molecular Systems Biology. Nature Microbiology. Meeussen J.V.W.

DNA 52

DNA RNA Engineering Licensing 52

Codon

APRIL 9, 2023

Marine sponges were cultured in the laboratory continuously for the first time. Sponge cells double in population quite quickly — around 40 minutes — and could be engineered to manufacture drugs. Read DNA Sequencing & Synthesis *Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing.

Therapies 52

Therapies RNA Engineering Vaccine 52

BMG Labtech

MARCH 8, 2023

DNA, proteins, polysaccharides, etc.). Cells require energy for this process. 2 Organisms are categorised based on their anabolism and according to the source used by cells to build-up molecules. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press. nucleotides, monosaccharides, etc.), doi:10.1101/glycobiology.3e.005

Molecular Biology 52

Molecular Biology Production Cell Based Assays Disease 52

Codon

SEPTEMBER 22, 2024

How Eggs and Sperm Get Made In the laboratory where I work, just down the street from the bustling Fenway Park in Boston, there is an incubator with a 96-well plate inside. Each well in the plate contains an ovarian organoid, a clump of cells similar to a miniature ovary. The most important step seems to be erasing DNA methylation.

DNA 106

DNA Laboratories Regulations Therapies 106

Codon

APRIL 16, 2023

Short DNA strands were discovered that can specifically and tightly bind to zinc and cadmium ions. Perhaps there is now a way to use DNA to extract metals: You could fuse the DNA strands to an antibody, coat them onto electronics, and then use a column to isolate the DNA:metal compounds? Nature Chemical Biology.

Engineering 52

Engineering DNA RNA Science 52

Codon

NOVEMBER 1, 2024

Today, we are largely unable to predict the outcomes of even “simple” biological questions, such as, “If I take this gene from an Arabidopsis plant, and insert it into Escherichia coli , will the cell express the gene and make functional protein?” ” Nobody really knows without trying it out in the laboratory.

DNA 118

DNA RNA Molecular Biology Laboratories 118