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Women in STEM July: Meet Michelle Arkin

Drug Target Review

I was ‘pre-med’ and got really interested in the science and especially the integration of chemistry and art. I struggled with going to graduate school in art conservation science, ie, the science of art, or more general chemistry, and I decided to do chemistry because it had broader opportunities.

DNA 98
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#WhyIScience Q&A: A cell biologist now helps recent college graduates launch their scientific careers

Broad Institute

By Leah Eisenstadt March 25, 2024 Credit: Allison Colorado, Broad Communications Alex Navarro, Senior Program Coordinator for the Broad Biomedical Post-baccalaureate Scholars Program Alex Navarro didn’t always aspire to a career in science. in cell biology. It was fun to spend so much time watching cells divide.

Science 111
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AI At The Frontier: Empowering Early Career Professionals In Drug Discovery

Elrig

Rising from Research Scientist to Senior Scientist, I supported early-stage DD efforts within their Protein Science group, based in Cambridge, UK. My role involved generating and characterizing complex proteins critical for biological assay development, hit discovery, and structural biology.

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Precision Medicine in the Genomic Era

DrugBank

In contrast, non-coding mutations have effects on gene expression, transcript stability, and the physical state of the DNA itself (e.g., How data science and AI-based technologies impact genomics. Network expansion of genetic associations defines a pleiotropy map of human cell biology. Making 40 , 924–938 (2020).

Disease 98
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A research team searches for every gene that helps tumors evade immunotherapy

Broad Institute

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. Along the way, TIDE is showing how careful, systematic science at scale can quickly home in on promising drug targets.

Research 137
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What Limits a Genome’s Size?

Codon

And what they found, remarkably, is the world’s largest genome ; each fern cell contains 160.45 billion bases of DNA which, if unfurled, would extend for more than 100 meters—taller than the Statue of Liberty. billion bases of DNA, the human genome measures just 2 meters in length when stretched end-to-end.

DNA 62
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Fast Biology

Codon

Collecting the Numbers We can easily measure some things in biology yet struggle to measure others. Thanks to decades of progress in molecular sequencing technologies, it is simple to read out the order of nucleotides in a DNA sequence, for example, or to quantify messenger RNAs as they are made by a cell.

RNA 98