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How to advance AAV-based gene therapies

Drug Discovery World

The greater data translatability gives developers the confidence to progress the most promising treatments and reduces clinical failures, thereby slashing project costs and timelines. What’s more, rodents are used widely across preclinical R&D, so most drug development labs already have the infrastructure to utilise them.

Therapies 162
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A research team searches for every gene that helps tumors evade immunotherapy

Broad Institute

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. They are used to treat cancers including melanoma and non-small cell lung cancer, but work only for a small fraction of patients.

Research 137