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Women in Stem with Ashley Hall

Drug Target Review

I was sure that Biology would be my major, but it required studying maths, and this was my first obstacle. Ashley Hall, CDO of Reneo Pharmaceuticals Throughout my education I was discouraged by many around me. When I was studying cell biology, looking at how cells divide, I couldn’t fathom how math could possibly fit into that.

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Advanced 3D cell-based technologies

Drug Target Review

1,2 This miniature organ chip devices emulate 3D structures with tissue-specific cell types and recreating organ functional units in an in vitro setting to test the effects of drugs and detailed reviewed. The first successful chip adaptation to a lung model was first described in 2010 by Donald Ingber, a bioengineer at Wyss institute.

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How nucleolar stress accelerates aging in mice

Drug Target Review

Initial works from the lab concentrated on exploring the role of replicative stress in cancer and ageing, for which the group combined cell biology, mouse models and drug development projects. Among other discoveries, the group developed inhibitors of the ATR kinase and showed their potential for cancer therapy.

RNA 64
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Guest Blog: Reflecting on the 2024 Society of Toxicology of Canada Symposium, by Ria Falvo, Director, Reporting

Alta Sciences

A non-profit organization, STC was founded in 1965 with 15 scientists from Montral-based pharmaceutical companies. It owned the societal name of the Canadian Association for Research on Drug Safety. The STC is an intimate gathering of scientists with a fervor to acquire and apply knowledge in toxicology.

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AI At The Frontier: Empowering Early Career Professionals In Drug Discovery

Elrig

With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. Harini joined Serna Bio in early 2021 and has been an integral part of the multidisciplinary teamworking on target ID platform development to drug discovery.

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TACACICLIB, AUR-102, AURIGENE

New Drug Approvals

As such, it has been proposed that inhibiting CDK7 would provide a potent means of inhibiting cell cycle progression, which may be especially relevant given that there is compelling evidence from gene knockout studies in mice for lack of an absolute requirement for CDK2, CDK4 and CDK6 for the cell cycle at least in most cell types (M alumbres et al.,

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Discovering an Antimalarial Drug in Mao’s China

Codon

Department of Defense administered mefloquine, the synthetic drug developed at Walter Reed in the U.S., only issued “the strongest ‘black box’ warning” against the drug in 2013. have been poured into replicating work already done” by Chinese scientists decades ago. Nobody had an answer.

Drugs 137