Drug Target Review

JULY 13, 2023

The company developed methods to identify disease-driving condensates, model them, and create systems for effective drug discovery targeting these condensates. The aim is to establish condensate biology as a fundamental branch of cell biology – “cell biology 2.0”

Disease 98

Disease Small Molecule Cell Biology Drugs 98

Drug Target Review

SEPTEMBER 19, 2023

This major shift to the orthodox tradition of using animal experiments in drug testing dates back the Aristotle’s time and cemented 80 years ago with initial federal mandate of drug safety regulation of 1938.

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Animal Testing Clinical Trials Pharmaceutical Companies FDA 98

Drug Target Review

OCTOBER 31, 2023

When I was studying cell biology, looking at how cells divide, I couldn’t fathom how math could possibly fit into that. My undergraduate studies focused on biochemistry and cell biology, so very much STEM-based, but my professors and mentors noticed my penchant for critical thinking which led me to consider law.

Cell Biology 107

Cell Biology Pharmaceuticals Science Disease 107

NIH Director's Blog: Drug Development

SEPTEMBER 20, 2018

That includes those involved in regulating our appetites and our moods, via a class of G proteins known as inhibitory G proteins (G i ). They share a common architecture and bind a relatively limited number of intracellular signaling proteins called G proteins.

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Laboratories Research Drugs Regulations 52

DrugBank

JUNE 27, 2023

The general notion is that patients should be viewed individually, rather than strictly as members of some larger general population, and that their specific genetic background, environment, and lifestyle choices should be considered throughout drug development to the point of treatment and continuing patient care.

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Disease Treatment Drugs Clinical Trials 98

New Drug Approvals

JANUARY 9, 2024

As such, it has been proposed that inhibiting CDK7 would provide a potent means of inhibiting cell cycle progression, which may be especially relevant given that there is compelling evidence from gene knockout studies in mice for lack of an absolute requirement for CDK2, CDK4 and CDK6 for the cell cycle at least in most cell types (M alumbres et al.,

Production 62

Production DNA RNA Regulations 62

Broad Institute

NOVEMBER 21, 2024

said study senior author Brad Bernstein , an institute member at Broad and director of the Gene Regulation Observatory at Broad. “We We found that IDH mutations are like a ticking time bomb that allows brain tumor cells to grow slowly and hide from the immune system while they acquire more dangerous mutations. Nature Cancer.

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Research Medical Schools DNA Hospitals 124