Cell Biology Drugs Immune Response 
Drug Target Review
OCTOBER 16, 2023
How can PDOs revolutionise drug discovery and deepen our understanding of disease? Patient-derived organoids (PDOs) are proliferative 3D cell structures derived from tissue samples of both healthy and diseased tissue. What sets PDOs apart from traditional 2D cell and animal models used in drug discovery?
The Pharma Data
JANUARY 3, 2021
Dr. Zeldis, who formerly served as Chief Medical Officer (CMO) and Head of Clinical Research, Medical Affairs, and Drug Safety, at Celgene, and CEO of Celgene Global Health, helped guide Celgene’s expansion into one of the biotechnology industry’s most successful companies. . GAITHERSBURG, Md.,
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Broad Institute
OCTOBER 11, 2023
By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. They are used to treat cancers including melanoma and non-small cell lung cancer, but work only for a small fraction of patients.
Drug Target Review
OCTOBER 2, 2024
Cardiovascular diseases are the leading cause of mortality worldwide, and traditional approaches like drug therapy or invasive procedures manage symptoms but do not restore lost cardiac tissue. While commonly used, AAVs have limitations, including immune reactions and difficulties with re-dosing due to pre-existing antibodies.
The Pharma Data
DECEMBER 31, 2020
“Antibody responses are not likely to be the sole determinant of someone’s outcome,” said Scott Boyd, associate professor of pathology at Stanford. Some of these patients mount a vigorous immune response, and others have a more moderate response. There are also other branches of the immune system involved.
Codon
APRIL 30, 2023
In one experiment, the microneedle patches were used to deliver a SARS-CoV-2 vaccine into mice, producing immune responses similar to a traditional injection. Printed vaccines caused mice to have a faster immune response. Nature Cell Biology. But the printed vaccines are very good! Cecilia Manduca on Medium.
Codon
APRIL 30, 2023
In one experiment, the microneedle patches were used to deliver a SARS-CoV-2 vaccine into mice, producing immune responses similar to a traditional injection. Printed vaccines caused mice to have a faster immune response. Nature Cell Biology. But the printed vaccines are very good! Cecilia Manduca on Medium.
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