Drug Target Review

AUGUST 10, 2023

When bound to GRP78, ID2 loses its inhibitory function, leading to increased invasiveness of cancer cells. Implications for cancer therapeutics and beyond These findings have wide-ranging implications for cancer treatment and cell biology research.

Cell Biology 52

Cell Biology Small Molecule Regulations Engineering 52

NIH Director's Blog: Drug Discovery

APRIL 11, 2017

Not only does this discovery raise hope for better treatments for many parasitic and bacterial diseases, it highlights the value of screening peptides in the search for ways to treat conditions that do not respond well—or have stopped responding—to more traditional chemical drug compounds. All of their hard work came up empty.

Small Molecule 52

Small Molecule Science Drug Development Disease 52

Drug Target Review

DECEMBER 21, 2023

Where do you see the future of mRNA biology and AI converging, and how does Anima Biotech plan to lead this convergence? mRNA biology has become widely recognised as a new “drug mine” RNAi drugs are in the market and mRNA vaccines, initially developed for Covid-19, are already in trials for cancer.

Disease 105

Disease Small Molecule Vaccine Drugs 105

Codon

APRIL 2, 2023

An open-source FACS automation system for high-throughput cell biology. Cell Systems. Read Small-molecule aptamer for regulating RNA functions in mammalian cells and animals. Read The FDA is reviewing a “controversial cell therapy for ALS,” developed by BrainStorm Cell Therapeutics.

DNA 52

DNA RNA Engineering Licensing 52

Codon

APRIL 30, 2023

Read Stem cells were induced to form insulin-secreting pancreas cells and then transplanted into diabetic mice, where they successfully restored glucose levels. Nature Cell Biology. Read Microbes in the wild ‘talk’ to their neighbors by emitting, and sensing, small chemicals. Cell Systems.

Vaccine 52

Vaccine DNA Engineering RNA 52

Codon

APRIL 30, 2023

Read Stem cells were induced to form insulin-secreting pancreas cells and then transplanted into diabetic mice, where they successfully restored glucose levels. Nature Cell Biology. Read Microbes in the wild ‘talk’ to their neighbors by emitting, and sensing, small chemicals. Cell Systems.

Vaccine 52

Vaccine DNA Engineering RNA 52

Drug Target Review

JANUARY 16, 2025

What are macrocycles and why are they interesting for drug discovery? Traditionally, drug discovery has focused on small-molecule therapeutics, typically with a molecular weight of less than 500 Daltons. 2 Typically, small-molecule drugs target active sites buried inside proteins.

Drug Development 52

Drug Development Small Molecule Drugs FDA Approval 52

Codon

APRIL 16, 2023

Nature Cell Biology. Read *Open-endedness in synthetic biology: a route to continual innovation for biological design. Read Local generation and efficient evaluation of numerous drug combinations in a single sample. Read Vitarka Therapeutics, a company developing a non-viral drug delivery technology, raised £1.27

Engineering 52

Engineering DNA RNA Science 52

Drug Target Review

MARCH 26, 2025

3 The scalable production of oestrogen led to its popularity and by the 1980-1990s, oestrogen (Premarin) was named the number one drug prescribed in the US. Hormone replacement requires treatment for the rest of a persons life thus, the greater the patient burden and number of side effects with a given drug, the lesser the compliance.

Therapies 52

Therapies Compliance Treatment Small Molecule 52