Drug Target Review

JULY 13, 2023

The aim is to establish condensate biology as a fundamental branch of cell biology – “cell biology 2.0” The underlying biology and processes upon which the company was founded have broad applicability across various human disease areas. Klein notes the importance of Dewpoint’s disease-agnostic approach.

Disease 98

Disease Small Molecule Cell Biology Drugs 98

Drug Target Review

JULY 23, 2024

Shortly after finishing my studies, I landed my first job in industry working on cell biology research for several disease indications. With these newer programs, I’ve had the honour of collaborating with my team to build a multi-faceted drug discovery engine.

Small Molecule 116

Small Molecule Targeted Protein Degradation Science Disease 116

Drug Target Review

AUGUST 10, 2023

Researchers from the Keck School of Medicine of USC used imaging techniques to study how the protein GRP78 controls cancer cell behavior. In the top row, human lung cancer cells were engineered to over-express GRP78 in the nucleus. In the bottom row, cells lacked GRP78 in the nucleus.

Cell Biology 52

Cell Biology Small Molecule Regulations Engineering 52

Drug Target Review

JULY 31, 2023

I went to Genentech and postdoc-ed for Jim Wells in protein engineering. If you are collaborating with all of these different people, if you’re providing the small molecule tools for lots of different projects, how can I evaluate you as an independent scientist?” That was a very hot field and a really exciting area.

DNA 98

DNA Small Molecule Science Cell Biology 98

The Pharma Data

OCTOBER 19, 2020

At Aduro, he was responsible for all manufacturing and supply chain activities for the company’s biologics and small molecules and managed a transatlantic team. Earlier in his career, he held development and engineering positions at BAC, part of Life Technologies, Unilever, and Crucell. in Cell Biology from Utrecht University.

Trials 40

Trials Small Molecule Cell Biology Clinical Trials 40

Codon

APRIL 2, 2023

This is Codon Digest, a weekly roundup of research papers, news articles, and industry highlights about engineered biology. ” — Samuel Butler , 1878 (* = My picks) AI + Bio Characterizing the interaction conformation between T-cell receptors and epitopes with deep learning. Thanks for skimming. Gungabeesoon J.

DNA 52

DNA RNA Engineering Licensing 52

Codon

APRIL 30, 2023

Read more at Nature Biotechnology ( Similar paper at Nature Biomedical Engineering.) How to make a cell-penetrating Cas9 protein, and then incubate it with peptides to edit human cells. 2/ Live Long and Prosper, Lil’ Yeasty Boys Yeast cells usually live for about one week. Nature Biomedical Engineering.

Vaccine 52

Vaccine DNA Engineering RNA 52