Cell Biology, FDA Approval and Small Molecule

Codon Digest: Injected Gene Editors

Codon

APRIL 2, 2023

An open-source FACS automation system for high-throughput cell biology. Cell Systems. Read Small-molecule aptamer for regulating RNA functions in mammalian cells and animals. Read The FDA is reviewing a “controversial cell therapy for ALS,” developed by BrainStorm Cell Therapeutics.

DNA

DNA RNA Engineering Licensing

Obstacles and innovations of macrocyclic drug development

Drug Target Review

JANUARY 16, 2025

Traditionally, drug discovery has focused on small-molecule therapeutics, typically with a molecular weight of less than 500 Daltons. 2 Typically, small-molecule drugs target active sites buried inside proteins. What are macrocycles and why are they interesting for drug discovery?

Drug Development

Drug Development Small Molecule Drugs FDA Approval

Drug Discovery Digest

Codon Digest: Injected Gene Editors

Obstacles and innovations of macrocyclic drug development

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