Drug Target Review

APRIL 12, 2024

Starting from a single cell rather than bulk cells eliminates the need for post-transfection cell sorting, saving hands-on time and ensuring 100 percent monoclonality. This holds particular significance, as it is a prerequisite for FDA approval in biotechnology that any cell clones must originate from a single-cell progenitor.

Cell Biology 105

Cell Biology FDA Approval FDA Research 105

Drug Target Review

APRIL 12, 2024

Starting from a single cell rather than bulk cells eliminates the need for post-transfection cell sorting, saving hands-on time and ensuring 100 percent monoclonality. This holds particular significance, as it is a prerequisite for FDA approval in biotechnology that any cell clones must originate from a single-cell progenitor.

Cell Biology 98

Cell Biology FDA Approval FDA Research 98

Drug Target Review

JUNE 5, 2023

It also supports the argument for developing ZW171 for the treatment of other MLSN-expressing solid tumours. What is the significance of ZW191 demonstrating strong responses in FRα-low expressing PDX models for the treatment of oncology indications with lower levels of FRα?

Treatment 100

Treatment Pharmacokinetics Drugs Cell Biology 100

Broad Institute

OCTOBER 11, 2023

By Allessandra DiCorato October 11, 2023 In 2011, Robert Manguso was working in a cell biology lab when his mother was diagnosed with Merkel cell carcinoma, a rare and aggressive skin cancer. When I began my PhD I completely switched my focus, and I haven’t looked back,” said Manguso.

Research 137

Research Immune Response Clinical Trials Therapies 137

Codon

APRIL 2, 2023

Mice and human cells that were given the therapy had normal levels of the survival motor neuron protein, and no symptoms. When delivered using AAV9 in mice, the treatment significantly improved motor function and extended average lifespan. An open-source FACS automation system for high-throughput cell biology. Wiener D.M.

DNA 52

DNA RNA Engineering Licensing 52

The Pharma Data

NOVEMBER 17, 2021

Now, new research led by investigators at Harvard Medical School and Boston Children’s Hospital points to a well-known and widely available drug called disulfiram as a possible treatment for COVID-19. The drug is FDA-approved and has been prescribed for over 60 years as a treatment for alcoholism.

Virus 52

Virus Drugs Clinical Trials Medical Schools 52

Codon

NOVEMBER 1, 2024

Amodei also imagines the ways AI could accelerate biological research and yield miraculous cures in the 21st century; everything from the prevention and treatment of nearly all infectious and inherited diseases to the elimination of most cancers. Today, a single injection of an FDA-approved gene therapy, called Hemgenix , cures this disease.

DNA 128

DNA RNA Molecular Biology Laboratories 128