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Researchers reveal regenerative potential of the thymus

Drug Discovery World

Roberta Ragazzini, Postdoctoral Research Associate at the Crick and UCL, and first author of the paper, said: “It’s paradoxical that stem cells in the thymus – an organ which reduces in size as we get older – regenerate just as much as those in the skin – an organ which replaces itself every three weeks.

Research 147
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CAR-NK cells: promising for cancer therapy

Drug Target Review

NK cells are among the front line of protection from infected and abnormal cells as part of the ‘innate immune response’. They recognise ‘cell stress molecules’ on the surface of infected, old, injured and cancerous cells without the need for complex pre-stimulation signals of the adaptive immune system (eg, T cells).

Therapies 118
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What to expect from PEGS Europe 2023: Day 3

Drug Discovery World

Enkelejda Miho, PhD, Professor, University of Applied Sciences and Arts Northwestern Switzerland, and Managing Director, aiNET, on: ‘The singular immune response to dengue and machine learning identification of antibodies in high-throughput sequences’.

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What to expect from PEGS Europe 2023: Day 1

Drug Discovery World

The luncheon presentation will be done by James Keck, PhD, President’s Innovation Fellow and Senior Director, Innovation and Product Development, Product Development, The Jackson Laboratory. He will cover the evaluation of safety and efficacy of antibody therapies in PBMC humanised mice.

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Codon Digest: CAR-T Therapy for Neuroblastoma

Codon

Marine sponges were cultured in the laboratory continuously for the first time. Sponge cells double in population quite quickly — around 40 minutes — and could be engineered to manufacture drugs. Nature Cell Biology. The RNA strands shut down a specific gene in the insects, and killed half after 7 days.

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Codon Digest: GPT-4 Controls a Robot

Codon

This looks like an early step toward a much different future for biology: One in which natural language is used to design experiments, program robots, and automate experiments in high-throughput. Skin microbes can trigger strong immune responses. epidermidis , can actually trigger tumor-specific T cells. Nature Protocols.