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Researchers reveal regenerative potential of the thymus

Drug Discovery World

Roberta Ragazzini, Postdoctoral Research Associate at the Crick and UCL, and first author of the paper, said: “It’s paradoxical that stem cells in the thymus – an organ which reduces in size as we get older – regenerate just as much as those in the skin – an organ which replaces itself every three weeks.

Research 147
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Codon Digest: Vaccine Printer Go Brrrrr!

Codon

Also, last week’s digest had an error: The country that approved the malaria vaccine was Ghana. 🔥 Five Amazing Things (That happened this week…) 1/ CRISPR Protein Penetrates Cells Not one, but two new papers report a better way to deliver Cas9 or Cas12 gene-editing proteins into living cells. Things are good.

Vaccine 52
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Codon Digest: Vaccine Printer Go Brrrrr!

Codon

Also, last week’s digest had an error: The country that approved the malaria vaccine was Ghana. 🔥 Five Amazing Things (That happened this week…) 1/ CRISPR Protein Penetrates Cells Not one, but two new papers report a better way to deliver Cas9 or Cas12 gene-editing proteins into living cells. Things are good.

Vaccine 52
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What to expect from PEGS Europe 2023: Day 1

Drug Discovery World

On Day 1, Tuesday 14 November 2023, the tracks include: Display of biologics, antibody-based cancer therapies, safety and efficacy of bispecific antibodies, modulating the tumour microenvironment, optimisation and developability, and cell line and systems engineering. from engineered peptide and antibody libraries’.

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What to expect from PEGS Europe 2023: Day 3

Drug Discovery World

Enkelejda Miho, PhD, Professor, University of Applied Sciences and Arts Northwestern Switzerland, and Managing Director, aiNET, on: ‘The singular immune response to dengue and machine learning identification of antibodies in high-throughput sequences’. It is called, ‘An unexpected future for immune oncology therapies?’

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Codon Digest: CAR-T Therapy for Neuroblastoma

Codon

“Computer science is to biology what calculus is to physics.” ” — Harold Morowitz 🔥 Ten Amazing Things (that happened this week…) A CAR-T therapy was tested in 27 children with neuroblastomas. The CAR-T cells were detectable in 26 out of 27 children after 30 months. Molecular Therapy.

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Codon Digest: GPT-4 Controls a Robot

Codon

This looks like an early step toward a much different future for biology: One in which natural language is used to design experiments, program robots, and automate experiments in high-throughput. Skin microbes can trigger strong immune responses. epidermidis , can actually trigger tumor-specific T cells. Cell Reports.