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The research scientist at the Max Planck Institute for Medical Research received the award in recognition of his ground-breaking work in establishing various approaches to protein labeling in living cells that have enabled far-reaching advances in chemical and cellbiology. Protein labeling (e.g.
“With the help of advanced laboratory techniques, we were able to identify a panel of nanobodies that very effectively neutralized several variants of SARS-CoV-2,” says Gerald McInerney, professor at the Department of Microbiology, Tumor and CellBiology (MTC), Karolinska Institutet, and joint senior author of both studies.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press. Alberts B, How Cells Obtain Energy from Food, MolecularBiology of the Cell (4th ed.). Alberts B, 2002, Energy Conversion: Mitochondria and Chloroplasts, MolecularBiology of the Cell (4th ed.). doi:10.1101/glycobiology.3e.005
Today, we are largely unable to predict the outcomes of even “simple” biological questions, such as, “If I take this gene from an Arabidopsis plant, and insert it into Escherichia coli , will the cell express the gene and make functional protein?” ” Nobody really knows without trying it out in the laboratory.
In this blog, we look at some of the ways a microplate reader can be used to advance protein nitration and related research in the laboratory. 1,2 Protein nitration is a post-translational modification that occurs in both prokaryotic and eukaryotic cells primarily on tyrosine residues.
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