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New molecular insights on medical cannabis

Drug Target Review

2,8-10 However, the number of compounds with satisfying pharmacokinetic parameters (PKD) are limited, with most unable to cross the blood-brain barrier or go sufficiently deep into a malignant tumour. Recently, our laboratory discovered a potent partial inhibition of ATX by cannabinoids in a nanomolar range. 2002 Jul 22;158(2):227–33.

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Advanced 3D cell-based technologies

Drug Target Review

Some of the complex 3D models such as organoids and organ-on-chips have brought in realistic make-over to the drug screening and paved way into implementing high content screening, laboratory automation and miniaturisation in primary drug screening process. From 3D cell culture to organs-on-chips. Trends in Cell Biology.

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Codon Digest: Injected Gene Editors

Codon

A giant dataset about the rat brain, and how neurons connect to each other, was collected and pooled together from 20 different research laboratories. An open-source FACS automation system for high-throughput cell biology. “Human cells hacked to act like squid skin cells could unlock key to camouflage.”

DNA 52