Drug Target Review

JULY 13, 2023

The aim is to establish condensate biology as a fundamental branch of cell biology – “cell biology 2.0” The underlying biology and processes upon which the company was founded have broad applicability across various human disease areas. Klein notes the importance of Dewpoint’s disease-agnostic approach.

Disease 98

Disease Small Molecule Cell Biology Drugs 98

Drug Target Review

SEPTEMBER 19, 2023

This major shift to the orthodox tradition of using animal experiments in drug testing dates back the Aristotle’s time and cemented 80 years ago with initial federal mandate of drug safety regulation of 1938. From 3D cell culture to organs-on-chips. Trends in Cell Biology. 2010;328(5986):1662-8. 2011;21(12):745-54.

Animal Testing 98

Animal Testing Clinical Trials Pharmaceutical Companies FDA 98

NIH Director's Blog: Drug Development

SEPTEMBER 20, 2018

That includes those involved in regulating our appetites and our moods, via a class of G proteins known as inhibitory G proteins (G i ). They share a common architecture and bind a relatively limited number of intracellular signaling proteins called G proteins. 2011 Jul 19;477(7366):549-55.

Laboratories 52

Laboratories Research Drugs Regulations 52

Codon

APRIL 9, 2023

Marine sponges were cultured in the laboratory continuously for the first time. Sponge cells double in population quite quickly — around 40 minutes — and could be engineered to manufacture drugs. Read Probe-based bacterial single-cell RNA sequencing predicts toxin regulation. Current Biology.

Therapies 52

Therapies RNA Engineering Vaccine 52

Codon

APRIL 2, 2023

A giant dataset about the rat brain, and how neurons connect to each other, was collected and pooled together from 20 different research laboratories. An open-source FACS automation system for high-throughput cell biology. Cell Systems. “Human cells hacked to act like squid skin cells could unlock key to camouflage.”

DNA 52

DNA RNA Engineering Licensing 52

BMG Labtech

MARCH 8, 2023

Cell metabolism and disease Metabolic perturbations and metabolic reprogramming are associated with common human diseases. In fact, metabolism should not be considered as a self-regulating entity that is independent of other biological pathways. On the contrary, cell metabolism affects or is affected by a multitude of processes.

Molecular Biology 52

Molecular Biology Production Cell Based Assays Disease 52

Codon

SEPTEMBER 22, 2024

How Eggs and Sperm Get Made In the laboratory where I work, just down the street from the bustling Fenway Park in Boston, there is an incubator with a 96-well plate inside. Each well in the plate contains an ovarian organoid, a clump of cells similar to a miniature ovary. Sign up for Asimov Press.

DNA 112

DNA Laboratories Regulations Therapies 112