Drug Target Review

APRIL 9, 2024

In a previous study, we showed that these peptides decorate all cellular RNAs and thus impair the binding of RNA-binding proteins to RNA. Initial works from the lab concentrated on exploring the role of replicative stress in cancer and ageing, for which the group combined cell biology, mouse models and drug development projects.

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RNA Cell Biology Clinical Development Disease 64

Codon

APRIL 2, 2023

A giant dataset about the rat brain, and how neurons connect to each other, was collected and pooled together from 20 different research laboratories. Read A new DNA polymerase variant, called RT-KTq I614Y, can directly detect RNA modifications, including pseudouridine (Ψ) and queuosine (Q). Communications Biology.

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DNA RNA Engineering Licensing 52

Codon

APRIL 9, 2023

Small snippets of double-stranded RNA were sprayed onto hot pepper plants to control a pest, called Frankliniella occidentalis. The RNA strands shut down a specific gene in the insects, and killed half after 7 days. RNA may offer a safer form of pest control in the future. Nature Chemical Biology. Current Biology.

Therapies 52

Therapies RNA Engineering Vaccine 52

Codon

SEPTEMBER 22, 2024

How Eggs and Sperm Get Made In the laboratory where I work, just down the street from the bustling Fenway Park in Boston, there is an incubator with a 96-well plate inside. Each well in the plate contains an ovarian organoid, a clump of cells similar to a miniature ovary. Sign up for Asimov Press.

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DNA Laboratories Regulations Therapies 112

Codon

APRIL 16, 2023

Read RIP-PEN-seq identifies a class of kink-turn RNAs as splicing regulators. Nature Cell Biology. Read *Open-endedness in synthetic biology: a route to continual innovation for biological design. Read An RNA-based system to study hepatitis B virus replication and evaluate antivirals. Nature Biotechnology.

Engineering 52

Engineering DNA RNA Science 52

Codon

APRIL 8, 2025

The study of RNA tumor viruses revealed reverse transcriptase , an enzyme integral in studying RNA biology. These model microorganisms have long served as natural laboratories, allowing the decoding of life's fundamental principles while providing the very tools needed to study them. Subscribe to Asimov Press.

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RNA DNA Laboratories Virus 89

Codon

NOVEMBER 1, 2024

Today, we are largely unable to predict the outcomes of even “simple” biological questions, such as, “If I take this gene from an Arabidopsis plant, and insert it into Escherichia coli , will the cell express the gene and make functional protein?” ” Nobody really knows without trying it out in the laboratory.

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DNA RNA Molecular Biology Laboratories 122