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The aim is to establish condensate biology as a fundamental branch of cellbiology – “cellbiology 2.0” The underlying biology and processes upon which the company was founded have broad applicability across various human disease areas. Klein notes the importance of Dewpoint’s disease-agnostic approach.
Recently, our laboratory discovered a potent partial inhibition of ATX by cannabinoids in a nanomolar range. Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. The Journal of CellBiology. Umezu-Goto M, Kishi Y, Taira A, et al. 2017;2017:1–15.
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Experiments performed with the bacterium Streptococcus pneumoniae not only led to the discovery of DNA as the principal hereditary molecule but also yielded early tools for genetic engineering. The study of RNA tumor viruses revealed reverse transcriptase , an enzyme integral in studying RNA biology. Subscribe to Asimov Press.
The introduction of a nitro- group into a protein molecule is also implicated in different diseases including cardiovascular disease , lung disease, diabetes, cancer and some neurodegenerative conditions. The nitration of proteins can significantly modify both the structural and catalytic roles of these molecules. The assay (Fig.
Nature CellBiology. Read *Open-endedness in synthetic biology: a route to continual innovation for biological design. Read Postdocs who work in an HHMI laboratory now get a minimum salary of $70,000. Read RIP-PEN-seq identifies a class of kink-turn RNAs as splicing regulators. Nature Biotechnology. Nature Protocols.
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